Table 2 Association of potential variables on median total lymph node count in 449 patients with resected gastric adenocarcinoma
From: Insufficient lymph node assessment in gastric adenocarcinoma
Variables | Patients’ no. | Median total LNs examined (Q1, Q3) | P value |
|---|---|---|---|
Patients’ sex | |||
Male | 301 | 8 (3, 14) | |
Female | 148 | 8 (3, 13) | 0.964 |
Patients’ age | |||
< 60 years | 221 | 8 (3, 12) | |
≥ 60 years | 228 | 8 (3, 15) | 0.387 |
Primary tumor site | |||
Diffuse | 45 | 11 (5, 18) | |
Non diffuse | 388 | 7 (2, 12) | 0.298 |
Type of gastric surgery | |||
Total or near total gastrectomy | 246 | 10 (5, 17) | |
Partial or subtotal gastrectomy | 167 | 7 (3, 11) | 0.001 |
Primary tumor stage | |||
T1–2 | 69 | 7 (4, 11) | |
T3–4 | 348 | 9 (4, 15) | 0.024 |
Node stage | |||
N0–2 | 286 | 7 (4, 12) | |
N3 | 92 | 17 (11, 25) | < 0.001 |
Tumor size | |||
≤ 6 cm | 263 | 7.5 (4, 12) | |
> 6 cm | 124 | 12 (6, 19) | < 0.001 |
Neoadjuvant treatment | |||
Not received | 433 | 8 (4, 14) | |
Received | 16 | 5 (0, 6) | 0.132 |
Surgical margin status | |||
Free | 295 | 8 (4, 14) | |
Involved | 105 | 9 (5, 16) | 0.445 |
Tumor grade | |||
Grades I–II | 234 | 8 (3, 14) | |
Grade III | 198 | 8 (4, 13) | 0.567 |
Lymphatic-vascular invasion | |||
Negative | 112 | 8 (4, 13) | |
Positive | 297 | 8 (4, 14) | 0.590 |
Perineural invasion | |||
Negative | 140 | 7 (4, 12) | |
Positive | 268 | 9 (4, 16) | 0.039 |
Histologic form | |||
Diffuse type | 171 | 8 (4, 15) | |
Intestinal type | 229 | 8 (3, 13) | 0.372 |