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Table 4 Multivariate analysis of factors affecting OS and DFS

From: Clinico-pathological significance of immunohistochemically marked tumor-associated macrophage in classic Hodgkin lymphoma

  OS   DFS
HR 95.0% CI P HR 95.0% CI P
B symptoms 4.55 1.21–16.96 0.02* Bulky disease 1.22 0.24-6.06 0.8
Bulky disease 0.66 0.2–2.18 0.5 CD68 0.88
IPS ≥ 3 3.55 1.95–10.521 0.02* CD68 (score II) 0.83 0.12–5.8 0.85
CD163 0.003* CD68 (score III) 0.36 0.007–19.6 0.62
CD163 (score II) 1.78 0.41–7.74 0.44 CD163 0.3
CD163 (score III) 9.39 2.19–40.22 0.003* CD163 (score II) 2.0 0.3–13.1 0.47
   CD163 (score III) 25.5 0.41–1571.7 0.12
  1. OS overall survival, DFS disease-free survival, HR hazard ratio, CI confidence interval, IPS International Prognostic score