Table 3 Impact of different prognostic variables on survival outcome
Variables | No. of patients | Event-free survival at 60 months (5 years) | P | Overall survival at 60 months (5 years) | P |
|---|---|---|---|---|---|
Total | 30 | 29.8 | 30.9 | ||
Age | |||||
<5 years | 20 | 38.2 | 0.091 | 38.5 | 0.146 |
≥5 years | 10 | NA | NA | ||
Gender | |||||
Male | 18 | 29.6 | 0.864 | 30.0 | 0.984 |
Female | 12 | 30.9 | 34.7 | ||
Interval between diagnosis and relapse | |||||
≤12 months | 13 | 44.9 | 44.9 | 0.478 | |
>12 months | 17 | 16.8 | 0.685 | 18.4 | |
Interval between nephrectomy and relapse | |||||
<12 months | 13 | 44.9 | 0.685 | 44.9 | 0.478 |
> = 12 months | 17 | 16.8 | 18.4 | ||
No. of adverse prognostic factors | |||||
1 and 2 | 15 | 19.3 | 0.920 | 21.1 | 0.821 |
3,4, and 5 | 15 | 38.9 | 38.9 | ||
Initial metastatic status | |||||
No | 22 | 37.8 | 0.129 | 37.8 | 0.145 |
Yes | 8 | NA | NA | ||
Initial pathology | |||||
Favorable | 24 | 30.3 | 0.647 | 31.5 | 0.681 |
Unfavorable | 6 | NA | NA | ||
Initial systemic stage | |||||
I, II | 10 | 45.0 | 0.565 | 45.0 | 0.511 |
III | 12 | 28.1 | 28.1 | ||
IV | 8 | NA | NA | ||
Initial local stage | |||||
I | 7 | 47.6% | NA | 47.6 | NA |
II | 4 | 25.0 | NA | 25.0 | |
III | 19 | 21.8 | NA | 24.2 | |
Site of relapse | |||||
Local | 11 | 12.5 | 0.934 | 12.5 | 0.787 |
Distant | 10 | 33.3 | 40.0 | ||
Combined | 9 | 44.4 | 44.4 | ||
RTH in relapse** | |||||
No | 12 | 11.1 | 0.013 | 16.7 | 0.012 |
Yes | 18 | 41.9 | 41.9 | ||
Risk stratification | |||||
Standard | 10 | 57.1 | 0.029 | 57.1 | 0.035 |
High/very High | 20 | 15 | 17 | ||
Post-operative residual | |||||
No | 24 | 30.9 | 0.957 | 32.3 | 0.944 |
Yes | 5 | 25.0 | 25.0 | ||