Skip to main content

Table 4 Recurrent Wilms’ tumor: clinical evidence and studies reports

From: Relapsed Wilms’ tumor in pediatric patients: challenges in low- to middle-income countries—a single-center experience

Study (year)

Group

Patients

Chemotherapy

ASCT

EFS (%)

OS (%)

Ref.

Abu Gosh et al. (2002)

CCG

11

ICE

No (2)

3-year (63.6)

63

[21]

Campbell et al. (2004)

Chicago

13

7/13 cyclophosphamide–etoposide–carboplatin

No (1 or 2)

4-year (60)

73

[22]

Malogolowkin et al. (2007)

NWTS-5

60

Cyclophosphamide–etoposide carboplatin–etoposide

No

4-year (42.3)

48

[23]

Sprea co et al. (2008)

AIEOP

20

ICE

MEC (8/15)

3-year, 56

55

[24]

Hale et al. (2008)

UK CCLG

45

Cyclophosphamide–etoposide carboplatin–etoposide

Melphalan

 

66

[25]

  1. AIEOP Associazione Italiana Ematologia Oncologia Pediatrica, CCG Children’s Cancer Group, CCLG Children’s Cancer and Leukemia Group, ASCR autologous stem cell rescue; EFS event-free survival, ICE ifosfamide–carboplatin–etoposide, MEC: melphalan–etoposide–carboplatin, NWTS National Wilms Tumor Study, OS overall survival