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Table 1 Baseline characteristics of the study population

From: Irradiation free conditioning regimen is associated with high relapse rate in Egyptian patients with acute lymphoblastic leukemia following allogeneic hematopoietic stem cell transplantation

Variable

TBI/Cy (n = 78)

Bu/Cy (n = 41)

p value

*Age (years)

27.64 ± 7.67 (19–49)

27.46 ± 7.00 (19–41)

0.902

Recipient sex

 Males

 Females

56 (71.8)

22(28.2)

30 (73.2)

11(26.8)

0.873

Immunophenotype

   

 B

 T

52 (66.7)

26 (33.3)

27 (65.9)

14 (34.1)

0.929

Performance status

   

 0–1

 2

75 (96.2)

3 (3.8)

38 (92.7)

3 (7.3)

0.339

Ph chromosome status

   

 Negative

 Positive

60 (76.9)

18 (23.1)

32 (78)

9 (22)

0.889

Disease status at transplant

   

 CR 1

 ≥ CR 2

40 (51.3)

38 (48.6)

16 (39)

25 (61)

0.203

Pre-transplant Comorbidities

   

 No

 Yes

76 (85.9)

11 (14.1)

37 (90.2)

3 (9.8)

0.497

Donor sex

   

 Females

 Males

33 (42.3)

45 (57.7)

22 (53.7)

19 (64.3)

0.238

Donor/recipient CMV seropositivity

   

 Mismatched

 Matched

7 (9)

71 (91)

2 (4.9)

39 (95.1)

0.717

*Diagnosis to transplant lag period (month)

16.25

(14–137.3)

13.5 (4.9–73.2)

0.114

  1. *Values are expressed as mean (range) and n (%)