Table 6 Comparison between the studied groups according to regimen-related toxicity
Variable | TBI/Cy (n = 78) | Bu/Cy (n = 41) | p value |
|---|---|---|---|
Mucositis | 0.005 | ||
Negative | 27 (34.6) | 16 (39.0) | |
Mild | 12 (15.4) | 8 (19.5) | |
Moderate | 10 (12.8) | 13 (31.7) | |
Severe | 29 (37.2) | 4 (9.8) | |
Veno-occlusive disease | 0.691 | ||
Negative | 74 (94.9) | 38 (92.7) | |
Positive | 4 (5.1) | 3 (7.3) | |
Hemorrhagic cystitis | 0.100 | ||
Negative | 71 (91.0) | 33 (80.5) | |
Positive | 7 (9.0) | 8 (19.25) | |
Idiopathic pneumonitis | 0.278 | ||
Negative | 75 (96.2) | 41 (100.0) | |
Positive | 3 (3.8) | 0 (0.0) | |
Diffuse alveolar | 0.545 | ||
Negative | 76 (97.4) | 41 (100.0) | |
Positive | 2 (2.6) | 0 (0.0) | |
Osteoporosis | 0.116 | ||
Negative | 73 (93.6) | 41 (100.0) | |
Positive | 5 (6.4) | 0 (0.0) | |
Infections | 0.037 | ||
Negative | 40 (51.2) | 29 (70.7) | |
Bacterial | 34 (43.6) | 10 (24.5) | |
Fungal | 2 (2.6) | 1 (2.4) | |
Viral | 2 (2.6) | 1 (2.4) | |
CMV reactivation | 0.017 | ||
Negative | 73 (93.6) | 32 (78.0) | |
Positive | 5 (6.4) | 9 (22.0) |