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Table 3 Univariate and multivariable logistic regression analyses for response to therapy (achievement of CR)

From: Initial absolute monocyte count as an immune biomarker for clinical response in acute myeloid leukemia with monocytic differentiation

Covariates

Univariate analysis

Multivariate analysis

OR (95% CI)

P

OR (95% CI)

P

Age (> 60Y vs. ≤ 60Y)

3.00 (0.50–17.95)

0.229

  

Sex (Male vs. Female)

1.00 (0.35–2.88)

1

  

PS (> 1 Y vs. ≤ 1)

2.33 (0.58–9.43)

0.234

  

FAB (M4 vs. M5)

0.91 (0.29–2.82)

0.869

  

Intensive induction (yes vs no)

4.33 (1.31–14.31)

0.016

5.67 (1.48–21.71)

0.011

Initial peripheral blast %

1.00 (0.98–1.02)

0.948

  

Initial bone marrow blast %

1.00 (0.97–1.02)

0.779

  

Initial TLC × 109/L

1.02 (1.00–1.04)

0.069

  

Monocytopenic (yes vs. no)

3.86 (1.21–12.28)

0.022

5.04 (1.37–18.58)

0.015

Cytogenetics (favorable vs others)

0.00 (0.0001–0.002)

0.999

  
  1. PS performance status, FAB French-American-British, TLC total leucocytic count, OR odds ratio, 95% CI 95% confidence interval