Journal of the Egyptian National Cancer Institute

Table 4 Analysis of receiver operating characteristic (ROC) curves of serum markers and their combinations

From: Identification of serum biomarker panel to differentiate malignant from benign thyroid nodules using multiplex bead assay

	AUC	95% CI
	AUC	LL	UL
IL-8	0.849	0.732	0.966
EGF	0.848	0.716	0.979
HGF	0.728	0.570	0.885
MIG	0.726	0.565	0.887
Ang-1	0.725	0.565	0.885
IL-8 + EGF	0.848	0.730	0.965
IL-8 + EGF + MIG	0.858	0.742	0.973
IL-8 + EGF + HGF	0.848	0.729	0.966
IL-8 + EGF + Ang-1	0.843	0.719	0.966
IL-8 + EGF + MIG + HGF	0.858	0.743	0.972

Ang-1 angiopoietin-1, AUC area under the curve, CI confidence intervals, EGF epidermal growth factor, HGF hepatocyte growth factor, IL-8 interleukin-8, MIG monokine induced by interferon gamma, LL lower limit, UL upper limit

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