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Table 4 Analysis of receiver operating characteristic (ROC) curves of serum markers and their combinations

From: Identification of serum biomarker panel to differentiate malignant from benign thyroid nodules using multiplex bead assay

  AUC 95% CI
LL UL
IL-8 0.849 0.732 0.966
EGF 0.848 0.716 0.979
HGF 0.728 0.570 0.885
MIG 0.726 0.565 0.887
Ang-1 0.725 0.565 0.885
IL-8 + EGF 0.848 0.730 0.965
IL-8 + EGF + MIG 0.858 0.742 0.973
IL-8 + EGF + HGF 0.848 0.729 0.966
IL-8 + EGF + Ang-1 0.843 0.719 0.966
IL-8 + EGF + MIG + HGF 0.858 0.743 0.972
  1. Ang-1 angiopoietin-1, AUC area under the curve, CI confidence intervals, EGF epidermal growth factor, HGF hepatocyte growth factor, IL-8 interleukin-8, MIG monokine induced by interferon gamma, LL lower limit, UL upper limit