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Table 2 Comparison between the HCC and the normal control groups as regards the glutathione S-transferase P1 (GSTP1) phenotype

From: Relation between GSTP1 polymorphism and oxidative stress in patients with hepatocellular carcinoma

   

Group

p value

OR

95% CI for OR

Control (80)

Cases (99)

  

GSTP1

AA

N (%)

60 (75)

45 (45.5)

< 0.001

  
 

GA

N (%)

20 (25)

44 (44.4)

   
 

GG

N (%)

0 (0.0)

10 (10.1)

   

Recessive model (GSTP1)

AA

N (%)

60 (75)

45 (45.5)

< 0.001

3.6

Lower, 1.894

Upper, 6.843

 

GA&GG

N (%)

20 (25)

54 (54.4)

   

Dominant model (GSTP1)

AA&AG

N (%)

80 (100)

89 (89.9)

0.003

  
 

GG

N (%)

0 (0)

10 (10.1)

   

GSTP1 (mutant versus wild)

Mutant

N (%)

20 (25.0)

54 (54.5)

< 0.001*

  
 

Wild

N (%)

60 (75)

45 (45.5)

   
  1. GSTP1 glutathione S-transferase P1
  2. *Significant p value ≤ 0.05