Table 3 Comparison of the plasma levels of reduced glutathione with some prognostic factors of HCC
From: Relation between GSTP1 polymorphism and oxidative stress in patients with hepatocellular carcinoma
GSH (μM/mg) (N: 684-2525) | Adjusted p value | ||
|---|---|---|---|
Median (range) | |||
Age (years) | < 54 | 1976 (862-3011) | 0.885 |
≥ 55 | 1861 (952-3000) | ||
Gender | Female | 1861 (877-2625) | 0.403 |
Male | 1952 (862-3011) | ||
Tumor size (cm) | 3 | 2013 (990-2409) | 0.891 |
Less than 3 | 1952 (877-2720) | ||
More than 3 | 1877 (862-3011) | ||
No. of masses | ≤ 3 | 1921 (867-3000) | 0.669 |
> 3 | 1889 (862-3011) | ||
Stage | Early stage | 1961 (867-3000) | 0.778 |
Late stage | 1912 (862-3011) | ||
Child score | A | 1991 (952-3000) | 0.043* |
B | 1952 (862-2720) | ||
C | 941 (894-987) | ||
Distant metastasis | No | 1919 (867-3011) | 0.333 |
Yes | 1247 (862-2931) | ||
Liver cirrhosis | Negative | 2568 (2124-3011) | * |
Positive | 1912 (862-3000) | ||
Portal vein | Thrombosed | 1689 (894-2911) | 0.859 |
Patent | 1988 (862-3011) | ||
Splenomegaly | −ve | 1746 (910-3000) | 0.455 |
+ve | 2003 (862-3011) | ||
Ascites | Present | 1731 (862-2416) | 0.043* |
Absent | 1952 (922-3011) | ||
L.Ns | −ve | 1914 (862-3011) | 0.369 |
+ve | 2061 (899-2931) | ||
Family history of HCC | Negative | 1912 (862-3011) | 0.448 |
Positive | 2000 (992-2911) | ||
HBV infection | B−ve | 1906 (862-3011) | 0.237 |
B + ve | 2101 (2003-2573) | ||
HCV infection | C−ve | 1838 (910-3011) | 0.905 |
C + ve | 1921 (862-3000) | ||
GSTP1 homo hetero vs wild | Mutant heterozygous | 1991 (877-2911) | 0.198 |
Mutant homozygous | 1508 (894-2241) | ||
Wild | 1851 (862-3011) | ||
GSTP1 wild vs mutant | Mutant | 1964 (877-2911) | 0.569 |
Wild | 1851 (862-3011) |