Systemic recurrence of endometrial cancer more than 10 years after hysterectomy: a report of two cases and a brief review of the literature

Table 1 Cases of late recurrence of endometrial carcinoma reported in literature

Study	Year	Age at recurrence	Histology of primary tumor	Stage (FIGO)	Primary surgery	Site of recurrence	Time to recurrence	Treatment of recurrence
Lederman et al.	1987	47	Adenoacanthoma	IA	H	Vagina	26 years	Radiotherapy
Ito et al.	2001	60	Adenoacanthoma	IB	H	Lung	17 years	Surgery
Lorenz et al.	2004	73	Endometrial carcinoma	IA	H	Abdominal scar	14 years	Surgery
Tsurumaki et al.	2009	72	Endometrioid adenocarcinoma	II	H + L	Ureter	11 years	Surgery + radiotherapy
Yechieli et al.	2011	61	Endometrioid adenocarcinoma	IC	H + BSO + L	Vagina	17 years	Brachytherapy
Addison et al.	2012	62	Endometrial carcinoma	IB	H + BSO	Appendix	10 years	Surgery
Franchello et al.	2015	72	Endometrioid adenocarcinoma	IB	H + BSO + L	Rectum	28 years	Surgery
Case report 1		56	Endometrial carcinoma	IB	H + BSO	Lung	16 years	Surgery + CT + HT
Case report 2		75	Endometrial carcinoma	II	H + BSO + L	Lung and soft tissues	22 years	Surgery + CT

H hysterectomy, BSO bilateral salpingo-oophorectomy, L lymphadenectomy, CT chemotherapy, HR hormone therapy