Table 6 Multivariate analysis of clinicopathological data and CD163 positive TAMs within tumor stroma

Step 1

Nodal metastasis

0.114 (0.034–0.382)

<0.001*

Step 2

Nodal metastasis

0.121 (0.033–0.448)

0.002*

ER

8.859 (1.492–52.287)

0.016*

Step 3

Vascular invasion

0.085 (0.014–0.495)

0.006*

Nodal metastasis

0.091 (0.021–0.389)

0.001*

ER

25.52 (2.528–257.5)

0.006*

Step 4

Vascular invasion

0.028 (0.003–0.315)

0.004*

Nodal metastasis

0.071 (0.015–0.348)

0.001*

Molecular subtypes

0.082

 Luminal A

0.026 (0.001–2.381)

0.113

 Luminal B

0.009 (0.001–0.818)

0.041*

 Triple negative

Reference

ER

2.966 (0.147–59.96)

0.478

Step 5

Vascular invasion

0.026 (0.002–0.284)

0.003*

Nodal metastasis

0.068 (0.014–0.331)

0.001*

Molecular subtypes

0.009*

 Luminal A

0.008 (0.001–0.231)

0.005*

 Luminal B

0.003 (0.001–0.124)

0.002*

 Triple negative

Reference