From: Effect of melatonin supplementation in combination with neoadjuvant chemotherapy to miR-210 and CD44 expression and clinical response improvement in locally advanced oral squamous cell carcinoma: a randomized controlled trial
miRNA-210
Mean (SD)
Melatonin (n = 13)
Placebo (n = 12)
p
Before
162.8 (54.92)
175.2 (34.30)
0.767
After
53.8 (16.65)
53.5 (14.28)
Difference (after − before)
− 109.09 (51.62)
− 103.71 (36.24)