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Journal of the Egyptian National Cancer Institute
Fig. 1 | Journal of the Egyptian National Cancer Institute

Fig. 1

From: Drug delivery nanocarriers and recent advances ventured to improve therapeutic efficacy against osteosarcoma: an overview

Fig. 1

Targeting mechanisms of nanocarriers against cancer. a Passive targeting where NCs accumulated in tumors as a result of leaky blood vessels and impaired lymphatic drainage in tumor tissues (EPR effect). b Active targeting wherein NCs surface decorated with ligands interact with cancer cells and internalized via receptor-mediated endocytosis mechanism [32]

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