Table 2 Histopathological, IHC results, and molecular subgroups
No. (%) | |
|---|---|
Histopathological types | |
Classic medulloblastoma | 14 (35%) |
Desmoplastic/nodular medulloblastoma | 10 (25%) |
Large cell/anaplastic medulloblastoma | 16 (40%) |
Degree of anaplasia | |
Slight anaplasia | 7 (17.5%) |
Moderate anaplasia | 15 (37.5%) |
Severe anaplasia | 18 (45%) |
β-catenin expression | |
Positive nuclear expression | 4 (10%) |
Negative both nuclear and cytoplasmic expression | 4 (10%) |
Cytoplasmic expression | 32 (80%) |
GAB1 expression | |
Negative | 28 (70%) |
Positive | 12 (30%) |
Molecular subgroups | |
WNT | 4 (10%) |
SHH | 12 (30%) |
Non-WNT/SHH | 24 (60%) |