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Table 2 Histopathological, IHC results, and molecular subgroups

From: Medulloblastoma: clinicopathological parameters, risk stratification, and survival analysis of immunohistochemically validated molecular subgroups

  No. (%)
Histopathological types  
Classic medulloblastoma 14 (35%)
Desmoplastic/nodular medulloblastoma 10 (25%)
Large cell/anaplastic medulloblastoma 16 (40%)
Degree of anaplasia  
Slight anaplasia 7 (17.5%)
Moderate anaplasia 15 (37.5%)
Severe anaplasia 18 (45%)
β-catenin expression  
Positive nuclear expression 4 (10%)
Negative both nuclear and cytoplasmic expression 4 (10%)
Cytoplasmic expression 32 (80%)
GAB1 expression  
Negative 28 (70%)
Positive 12 (30%)
Molecular subgroups  
WNT 4 (10%)
SHH 12 (30%)
Non-WNT/SHH 24 (60%)