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Fig. 2 | Journal of the Egyptian National Cancer Institute

Fig. 2

From: The role of PI3K signaling pathway and its associated genes in papillary thyroid cancer

Fig. 2

Cluster analysis of significant genes obtained from the meta-analysis approach for (a) GSE97001 and (b) GSE29265 datasets using Gene Cluster 3.0 and Java TreeView tools [14]. Upregulated genes with fold change combined values: LAMB3 (FC=23.836), COMP (FC=7.85), SPP1 (FC=3.605), TNC (FC=3.072), RBB3 (FC=2.842), CCND1 (FC=2.734), TLR2 (FC=2.591), CCND2 (FC=2.475), LAMC2 (FC=2.452), CDKN1A (FC=2.25), COL1A1 (FC=2.146); downregulated genes with fold change combined values: KIT (FC=9.05), PDGFRA (FC=4.126), IGF2 (FC=3.734), GHR (FC=3.626), BCL2 (FC=3.114), IRS1 (FC=3.038), LPAR1 (FC=2.67), FGF7 (FC=2.362), PGF (FC=2.31), FGFR2 (FC=2.245), PRKCA (FC=2.242), LAMA2 (FC=2.239), MYC (FC=2.025)

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