Skip to main content

Table 3 Association of acute oral mucositis with other toxicities

From: Post hoc analysis of a randomized controlled trial comparing concurrent chemoradiation with cisplatin versus nimotuzumab-cisplatin, focusing on acute oral mucositis

Adverse event

Grade of adverse event

Mucositis

p value

Grade 0–2

(n = 203)

Grade3-5

(n = 321)

Rise in serum creatinine

Any grade

17 (8.4%)

32(10%)

0.645

Grade 3–5

2(0.6%)

0.524

Odynophagia

Any grade

192(94.6%)

317(98.8%)

0.007

Grade 3–5

38(18.7%)

169(52.6%)

< 0.0001

Dysphagia

Any grade

160(78.8%)

295(91.9%)

< 0.0001

Grade 3–5

33(16.3%)

122(38.0%)

< 0.0001

Weight loss

Any grade

50(24.6%)

243(75.7%)

< 0.0001

Grade 3–5

0(0)

5(1.6%)

0.162

Dermatitis

Any grade

168(82.8%)

304(94.7%)

< 0.0001

Grade 3–5

38(18.7%)

111(34.6%)

< 0.0001