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Fig. 5 | Journal of the Egyptian National Cancer Institute

Fig. 5

From: Green tea catechins in combination with irinotecan attenuates tumorigenesis and treatment-associated toxicity in an inflammation-associated colon cancer mice model

Fig. 5

Effect of IRN and GT on A total number of WBC, B percentage of neutrophil, C serum ALT, and D serum creatinine level during the 12-week treatment period. Values were presented as mean ± SEM, #p < 0.05, ##p < 0.01, and ###p < 0.01 when compared to the PC group and *p < 0.05, **p < 0.01, and ***p < 0.001 when compared to the IRN group. Decrease in number of WBC was recorded in treated groups; however, decrease was recorded to be significant and maximum in the IRN group as compared to the PC group. Significant increase in number of neutrophil was recorded in the IRN+GTHigh group as compared to the IRN group. Significant increase in serum ALT level was recorded in the IRN group when compared to the PC group. ALT level was recorded to be less in the IRN+GTHigh group as compared to the IRN group. Decrease in serum creatinine level was recorded in treated groups; however, decrease was recorded to be maximum in the IRN+GTHigh group

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