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Table 2 Reverse virtual screening of Acetyl-keto-11-beta-boswellic acid (AKBA) and docetaxel (TXL) against αβ Tubulin

From: Chloroform extract and acetyl-11-keto-beta-boswellic acid from Boswellia dalzielii stem bark induce apoptosis and cell cycle blockage in AW8507 cells

Target protein PDB entry Ligand-protein complex Binding scores (kcal/mol)
αβ Tubulin 1TUB30 AKBA (up) = -8.9
   TXL (down) = -8.3
  1. In the structural depictions, AKBA (black) and TXL (red) occupy the defined active site of the target protein which is employed in its crystallographic state as retrieved from the protein data bank