Table 2 Correlation between different prognostic factors and survival
From: Prognostic factors and outcome of pineoblastoma: 10 years single-center experience
OS at 36 months (%) | 95% CI | P value | EFS at 36 months (%) | 95% CI | p value | |
|---|---|---|---|---|---|---|
Age | ||||||
< 3 years | 10 | 8.6–28.6 | 0.002 | 10 | 8.6–28.6 | 0.001 |
> 3 years | 65.2 | 43.8–86.6 | 59.9 | 37.8–82 | ||
Metastatic disease | ||||||
M0 | 54.5 | 28.8–80.2 | 0.16 | 49.9 | 24–75.2 | 0.17 |
M + ve | 37.3 | 11.2–63.4 | 37.3 | 11.2–63.4 | ||
Metastatic state in each age group: | ||||||
< 3 years | 16.7 | 0–46.2 | 0.2 | 16.7 | 0–46.2 | 0.13 |
> 3 years | 50 | 13–86.5 | 50 | 13.5–86.5 | ||
M0 in each group | ||||||
< 3 years | 0 | NA | 0.002 | 0 | NA | 0.001 |
> 3 years | 74 | 48.1–99.9 | 65.3 | 13.5–86.5 | ||
Extent of resection: | ||||||
GTR/NTR | 50 | 10–90 | 0.62 | 50 | 10–90 | 0.71 |
STR | 0 | NA | 0 | NA | ||
Biopsy | 50 | 28–72 | 46.8 | 25.2–68.4 | ||
Extent of surgery | ||||||
Less than 3 | ||||||
GTR/NTR | 0 | NA | 0.92 | 0 | NA | 0.87 |
Biopsy | 14.3 | 0–40.2 | 14.3 | 0–40.2 | ||
More than 3 | ||||||
GTR/NTR | 100 | NA | 0.11 | 100 | NA | 0.17 |
STR | 0 | NA | 0 | NA | ||
Biopsy | 66.9 | 42–91.8 | 59.6 | 33.1–86.1 | ||
Radiotherapy: | ||||||
Yes | 53.3 | 33.5–73.1 | < 0.001 | 50.7 | 31.1–70.3 | < 0.001 |
No | 0 | NA | 0 | NA | ||
Radiotherapy field: | ||||||
CSI | 65.2 | 43.8–86.6 | 0.04 | 59.9 | 37.8–82 | 0.02 |
Focal | 16.7 | 0–46.5 | 16.7 | 0–46.5 | ||
Chemotherapy: | ||||||
Yes | 51.5 | 31.9–71.1 | 49 | 43.8–86.6 | ||
No | 0 | NA | < 0.001 | 0 | NA | < 0.001 |
Radiological response | ||||||
CR | 75 | 29.6–90.4 | 62.5 | 29.6–90.4 | ||
PR | 60 | 50.5–99.5 | 60 | 32.1–92.9 | ||
MR | 0 | NA | 0.004 | 0 | NA | < 0.001 |
SD | 0 | NA | 0 | NA | ||
PD | 0 | NA | 0 | NA | ||