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Table 2 Correlation between different prognostic factors and survival

From: Prognostic factors and outcome of pineoblastoma: 10 years single-center experience

  OS at 36 months (%) 95% CI P value EFS at 36 months (%) 95% CI p value
Age
< 3 years 10 8.6–28.6 0.002 10 8.6–28.6 0.001
> 3 years 65.2 43.8–86.6   59.9 37.8–82  
Metastatic disease
M0 54.5 28.8–80.2 0.16 49.9 24–75.2 0.17
M + ve 37.3 11.2–63.4   37.3 11.2–63.4  
Metastatic state in each age group:
< 3 years 16.7 0–46.2 0.2 16.7 0–46.2 0.13
> 3 years 50 13–86.5   50 13.5–86.5  
M0 in each group
< 3 years 0 NA 0.002 0 NA 0.001
> 3 years 74 48.1–99.9   65.3 13.5–86.5  
Extent of resection:
GTR/NTR 50 10–90 0.62 50 10–90 0.71
STR 0 NA   0 NA  
Biopsy 50 28–72   46.8 25.2–68.4  
Extent of surgery
Less than 3
  GTR/NTR 0 NA 0.92 0 NA 0.87
  Biopsy 14.3 0–40.2   14.3 0–40.2  
More than 3
  GTR/NTR 100 NA 0.11 100 NA 0.17
  STR 0 NA   0 NA  
  Biopsy 66.9 42–91.8   59.6 33.1–86.1  
Radiotherapy:
Yes 53.3 33.5–73.1 < 0.001 50.7 31.1–70.3 < 0.001
No 0 NA   0 NA  
Radiotherapy field:
 CSI 65.2 43.8–86.6 0.04 59.9 37.8–82 0.02
 Focal 16.7 0–46.5   16.7 0–46.5  
Chemotherapy:
 Yes 51.5 31.9–71.1   49 43.8–86.6  
 No 0 NA < 0.001 0 NA < 0.001
Radiological response
 CR 75 29.6–90.4   62.5 29.6–90.4  
 PR 60 50.5–99.5   60 32.1–92.9  
 MR 0 NA 0.004 0 NA < 0.001
 SD 0 NA   0 NA  
 PD 0 NA   0 NA