Fig. 2

A Radical cystectomy specimen showing urinary bladder with a large necrotic and fungating growth arising from left lateral wall with serosal involvement. The resected hysterectomy specimen shows a leiomyoma. B Photomicrograph showing tumor with overlying urothelial epithelium. Eosinophilic spindle shaped tumor cells are arranged in storiform pattern and interlacing fascicles (H&E, × 40). C Tumor is infiltrating bladder muscle (H&E, × 40). D Immunohistochemistry (IHC) shows expression of smooth muscle actin (SMA) in the tumor cells (SMA immunostain, × 200). E Sections from intestinal mass showed an invasive well-demarcated tumor arising from muscularis mucosae and extending transmurally to reach the serosa. Photomicrograph shows spindle cell tumor arranged in short and long fascicles (H&E, × 40). F High magnification showing increased mitotic activity in the spindle shaped tumor cells (H&E, × 400). G On IHC, the tumor cells were negative for CD34, and H negative for DOG1