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Table 3 Association of clinicopathological characteristics and pCR

From: Pathological responses and survival outcomes in patients with locally advanced breast cancer after neoadjuvant chemotherapy: a single-institute experience

Variables

pCR events (%)

p-value*

Age

 ≤ 50 years

23/151 (15.23)

0.789

 > 50 years

21/128 (16.41)

 

cT1–2

21/72 (27.14)

0.026

cT3–4

14/100 (13.40)

 

cN0

9/25 (25.7)

0.111

cN1–3

26/123 (21.1)

 

HR+/HER2−

17/131 (13)

0.069

Other subtypes

25/116 (21.55)

 

Grade

 G2

28/173 (16.18)

0.136

 G3

6/21 (28.57)

 

LVI

 No

17/74 (22.97)

0.07

 Yes

3/35 (8.57)

 

Ki-67

 Low index

21/92 (22.83)

0.05

 High index

14/35 (41.18)

 

Neoadjuvant chemotherapy

 

0.014

 Optimal ≥ 6 cycles

34/153 (22.22)

 

 Suboptimal < 6 cycles

6/70 (8.57)

 
  1. *p-values were computed using the chi-square test