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Table 5 Univariate and multiple Cox regression analyses of predictors of disease-free survival

From: Pathological responses and survival outcomes in patients with locally advanced breast cancer after neoadjuvant chemotherapy: a single-institute experience

 

Hazard ratio

p-value

95% confidence interval

DFS (simple)

 Age group (≤ 50 vs. > 50)

0.694

0.075

0.464

1.03

 HR (positive)

0.561

0.008

0.37

0.86

 cT1, 2 vs. c T3, 4

0.0807

0.481

0.44

1.46

 N+ vs. N0

1.97

0.22

0.60

6.40

 ORR (yes)

0.38

0.04

0.02

0.96

 pCR (yes)

0.288

0.007

0.12

0.71

 HER2 (positive)

1.0404

0.9

0.56

1.93

 Optimal chemotherapy (yes)

0.5613

0.012

0.36

0.89

DFS (multiple)

 Age group (< 50 vs. > 50)*

0.42

0.004

0.23

0.76

 HR (positive)*

0.46

0.004

0.27

0.78

 pCR (yes)*

0.30

0.022

0.11

0.84

 Optimal chemotherapy (yes)*

0.52

0.022

0.29

0.91

  1. Significant p-value in bold
  2. DFS disease-free survival, HR hormone receptor, ORR objective response rate, pCR pathological complete response
  3. *These variables were included in the same multiple Cox regression model