Table 4 Expression of immunohistochemical markers in relation to histopathological types
From: Subtyping of high grade serous ovarian carcinoma: histopathological and immunohistochemical approach
| Â | Mesenchymal type N=25(%) | Proliferative type N=14(%) | Immunoreactive type N=14(%) | Differentiated type N=32(%) | Test of significance | |
|---|---|---|---|---|---|---|
SET features N=13(%) | Papillary features N=19(%) | |||||
Ki 67 | ||||||
 Low | 13 (52.0) | 0 (0.0) | 8 (57.1) | 13 (100.0) | 19 (100.0) | MC |
 High | 12 (48.0) | 14 (100.0) | 6 (42.9) | 0 (0.0) | 0 (0.0) | P<0.001* |
CD8 | ||||||
 Low | 15 (60.0) | 14 (100.0) | 0 (0.0) | 13 (100.0) | 19 (100.0) | MC |
 High | 10 (40.0) | 0 (0.0) | 14 (100.0) | 0 (0.0) | 0 (0.0) | P<0.001* |
ER | ||||||
 Negative | 11 (44.0) | 5 (35.7) | 7 (50.0) | 6 (46.2) | 15 (78.9) | χ2=7.85 |
 Positive | 14 (56.0) | 9 (64.3) | 7 (50.0) | 7 (53.8) | 4 (21.1) | P=0.097 |
PR | ||||||
 Negative | 22 (88.0) | 11 (78.6) | 14 (100.0) | 9 (69.2) | 18 (94.7) | MC |
 Positive | 3 (12.0) | 3 (21.4) | 0 (0.0) | 4 (30.8) | 1 (5.3) | P=0.105 |
Vimentin | ||||||
 Low | 11 (44.0) | 9 (64.3) | 8 (57.1) | 6 (46.2) | 12 (63.2) | χ2=2.63 |
 High | 14 (56.0) | 5 (35.7) | 6 (42.9) | 7 (53.8) | 7 (36.8) | P=0.623 |
E-cadherin | ||||||
 Negative | 24 (96.0) | 12 (85.7) | 13 (92.9) | 11 (84.6) | 18 (94.7) | MC |
 Positive | 1 (4.0) | 2 (14.3) | 1 (7.1) | 2 (15.4) | 1 (5.3) | P=0.66 |