Table 3 Diagnostic accuracy of symptom score in combination with CA125 in detecting ovarian malignancy
Sensitivity % (95% CI) | Specificity % (95% CI) | PPV %a (95% CI) | NPV %b (95% CI) | |
|---|---|---|---|---|
Symptom score≥9 | 84.8 (76.8–90.9) | 88.6 (83.8–92.4) | 78.5 (70.1–85.5) | 92.3 (87.9–95.4) |
Ca125≥35U/mL | 86.6 (78.9–92.3) | 69.9 (63.5–75.7) | 58.4 (50.5–66) | 91.4 (86.3–95.1) |
Symptom score≥9 or Ca125≥35U/mL | 96.4 (91.1–99) | 65.5 (59–71.6) | 57.8 (50.3–64.9) | 97.4 (93.5–99.3) |