Table 1 Surgical trials
From: Evolution of treatment in gastric cancer- a systematic review
TRIAL / AUTHOR | PURPOSE | RESULT |
|---|---|---|
Dutch, Bonenkamp et al | D1 VS D2 lymphadenectomy | Gastric cancer related death, Locoregional recurrence lower in D2 |
MRC, A Cushieri et al | D1 VS D2 lymphadenectomy | D2 has no survival benefit over D1 |
Italian gastric cancer study group, Degiuli et al | D1 VS D2 lymphadenectomy | D2 Lymphadenectomy can be safely performed comparable to D1 |
Wu et al. (Taiwan) | D1 VS D3 lymphadenectomy | D3 group has better overall survival |
JCOG 9501, Fujimura | D2 versus PAND lymphadenectomy | No benefit of PAND |
Marano et al | Bursectomy versus no bursectomy | Better Overall survival |
JCOG1001, Kurokawa et al | Bursectomy versus no bursectomy | No benefit |
JCOG 0110, Sano T et al | Splenectomy versus no splenectomy | No benefit of routine splenectomy |
JCOG 1711, ROAD -GC, Sato et al | Omentectomy versus no omentectomy | Ongoing |
KLASS 01, CLASS 02, JCOG 0912 | Laparoscopy versus Open distal gastrectomy (Early stage) | equivalent oncological outcomes |
KLASS03, Hyung et al | Laparoscopy versus Open total gastrectomy (Stage I) | equivalent oncological outcomes |
KLASS 02, CLASS 01 | Laparoscopy versus Open distal gastrectomy (Locally advanced)) | equivalent oncological outcomes |
JLSSG0901, katai et al | Laparoscopy versus Open total gastrectomy (Locally advanced) | Ongoing |