Table 3 Neoadjuvant/ Adjuvant Chemoradiotherapy
From: Evolution of treatment in gastric cancer- a systematic review
TRIAL / AUTHOR | PURPOSE | RESULT |
|---|---|---|
INT -0116/ Macdonald, JS et al., 2001 | Surgery + FL + RT vs Surgery | Better overall survival |
ARTIST/ Park SH et al., 2015 | XP + RT vs XP | No benefit of adding RT except in node positive disease |
CRITICS/ Cats et al., 2018 | Pre ECX (EOX) + Post RT + XP vs Peri ECX (EOX) | No benefit of adding RT |
ARTIST-2/ Park SH et al., 2019 | SOX + RT + S-1 vs SOX vs S-1 | No benefit of Adding adjuvant RT even in node positive patients |
CRITICS -2/ Slagter AE et al | DOC vs DOC + RT vs RT (All neoadjuvant) | Ongoing |
TOPGEAR/ Leong et al | Pre and Post op ECF vs Pre ECF + RT + Post ECF | Ongoing |