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Table 4 ROC curve analyses for the serum levels of miR10b and miR21 in patients with BC versus healthy controls

From: MicroRNA 21 and microRNA 10b: early diagnostic biomarkers of breast cancer in Egyptian females

 

AUC

P

95% CI

Cutoff

Sensitivity (%)

Specificity (%)

PPV

NPV

Accuracy

Lower bound

Upper bound

FC of miR10b

0.991

< 0.001

0.975

1.000

3.1545

97.1

100

100

90.9

97.7

FC of miR21

0.965

< 0.001

0.928

1.000

1.7582

95.7

85

95.7

85

93.3

  1. 95% CI confidence interval, PPV positive predictive value, NPV negative predictive value