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Table 1 Characteristics of the studies included in the meta-analysis

From: A microRNA binding site polymorphism in the 3′ UTR region of VEGF-A gene modifies colorectal cancer risk based on ethnicity: a meta-analysis

Authors name Year Technique Ethnicity Country No. of cases No. of control Case Control HWE
       CC CT TT CC CT TT  
Yang et al. [39] 2017 iMLDR East Asian China 371 246 243 118 10 180 62 4 0.74
Ahmad et al. [40] 2016 PCR/pyrosequencing Caucasian Sweden 150 150 114 29 7 101 47 2 0.17
Jannuzzi et al. [41] 2015 PCR/RFLP Caucasian Turkey 103 129 78 23 2 93 32 4 0.54
Credidio et al. [42] 2014 PCR/RFLP Caucasian Brazil 261 261 210 48 3 205 54 2 0.44
Lau et al. [43] 2014 TaqMan South Asian Malaysia 130 212 99 31 0 151 57 4 0.6
Jang et al. [44] 2013 Sequencing East Asian Korea 390 492 349 130 13 244 135 11 0.13
Antonacopoulou et al. [45] 2011 TaqMan Caucasian Greece 223 264 178 80 5 151 67 6 0.65
Wu et al. [46] 2011 TaqMan East Asian China 224 200 158 59 7 166 31 3 0.27
Wu et al. [47] 2009 PCR/RFLP Caucasian German 157 117 123 31 3 88 28 1 0.44
Ungerbäck et al. [48] 2009 SNuPe™ genotyping kit Caucasian Sweden 302 336 197 91 14 239 88 9 0.79
Bae et al. [49] 2008 PCR East Asian Korea 262 229 170 83 9 169 57 3 0.45
Chae et al. [50] 2008 PCR/DHPLC East Asian Korea 465 413 293 156 16 252 149 12 0.06
Hofmann et al. [51] 2008 TaqMan Caucasian Austria 427 427 331 88 8 308 108 11 0.67
  1. HWE Hardy–Weinberg equilibrium, iMLDR improved multiplex ligation detection reaction, RFLP restriction fragment length polymorphism, DHPLC denaturing high-performance liquid chromatography