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Table 1 Characteristics of the studies included in the meta-analysis

From: A microRNA binding site polymorphism in the 3′ UTR region of VEGF-A gene modifies colorectal cancer risk based on ethnicity: a meta-analysis

Authors name

Year

Technique

Ethnicity

Country

No. of cases

No. of control

Case

Control

HWE

      

CC

CT

TT

CC

CT

TT

 

Yang et al. [39]

2017

iMLDR

East Asian

China

371

246

243

118

10

180

62

4

0.74

Ahmad et al. [40]

2016

PCR/pyrosequencing

Caucasian

Sweden

150

150

114

29

7

101

47

2

0.17

Jannuzzi et al. [41]

2015

PCR/RFLP

Caucasian

Turkey

103

129

78

23

2

93

32

4

0.54

Credidio et al. [42]

2014

PCR/RFLP

Caucasian

Brazil

261

261

210

48

3

205

54

2

0.44

Lau et al. [43]

2014

TaqMan

South Asian

Malaysia

130

212

99

31

0

151

57

4

0.6

Jang et al. [44]

2013

Sequencing

East Asian

Korea

390

492

349

130

13

244

135

11

0.13

Antonacopoulou et al. [45]

2011

TaqMan

Caucasian

Greece

223

264

178

80

5

151

67

6

0.65

Wu et al. [46]

2011

TaqMan

East Asian

China

224

200

158

59

7

166

31

3

0.27

Wu et al. [47]

2009

PCR/RFLP

Caucasian

German

157

117

123

31

3

88

28

1

0.44

Ungerbäck et al. [48]

2009

SNuPe™ genotyping kit

Caucasian

Sweden

302

336

197

91

14

239

88

9

0.79

Bae et al. [49]

2008

PCR

East Asian

Korea

262

229

170

83

9

169

57

3

0.45

Chae et al. [50]

2008

PCR/DHPLC

East Asian

Korea

465

413

293

156

16

252

149

12

0.06

Hofmann et al. [51]

2008

TaqMan

Caucasian

Austria

427

427

331

88

8

308

108

11

0.67

  1. HWE Hardy–Weinberg equilibrium, iMLDR improved multiplex ligation detection reaction, RFLP restriction fragment length polymorphism, DHPLC denaturing high-performance liquid chromatography