Table 2 Genes involved in the signaling pathways targeted by 11 over-expressed miRs in PDAC attained with Ingenuity Pathway Analysis (IPA) [12]
From: Potential role of microRNAs in pancreatic cancer manifestation: a review
Signaling pathway | p-value | Ratio | Molecules |
|---|---|---|---|
PTEN signaling | 8.48E−05 | 5/123 (0.041) | RPS6KB1, INSR, CDKNIB, PTEN |
PIEK/AKT signaling | 1.66E−03 | 4/142 (0.028) | RPS6KB1, FOXO1, CDKNIB, PTEN |
Insulin receptor signaling | 2.20E−04 | 5/141 (0.035) | RPS6KB1, FOXO1, PPP1R11, INSR, PTEN |