Table 1 Clinical characteristics of GBM patients
Characteristics | N | % |
|---|---|---|
Total Patients | 55 | |
Age (Median: 50 years, range: 24-70 years) | ||
≤50 | 27 | 49 |
>50 | 28 | 51 |
Gender | ||
Female | 20 | 36 |
Male | 35 | 64 |
Tumor Location | ||
Frontal | 23 | 42 |
Temporal | 12 | 22 |
Parietal | 17 | 31 |
Occipital | 03 | 05 |
KPSa Score (Median: 60) | ||
High KPS:>60 | 31 | 56 |
Low KPS:<60 | 24 | 44 |
Treatment | ||
Only Surgery | 34 | 62 |
Followed by | ||
Radiotherapy (RT) | 04 | 07 |
Chemotherapy (CT) | 06 | 11 |
RT + CT | 11 | 20 |
Progression-free survival (n=34) | ||
Median 12 months | ||
GC well | 24 | 71 |
Recurrence | 10 | 29 |
Median 24 months | ||
GC well | 14 | 41 |
Recurrence | 20 | 59 |
Overall survival (n=34) | ||
Median-12 months | ||
Alive | 27 | 79 |
Died | 07 | 21 |
Median-24 months | ||
Alive | 11 | 32 |
Died | 23 | 68 |
IDH1/2 Mutations | ||
Absent | 30 | 55 |
Present | 25 | 45 |
STAT3 gene expression | ||
Normal Expression | 08 | 15 |
Altered expression | 47 | 85 |
Down regulation | 23 | 49 |
Up-regulation | 24 | 51 |