From: Analysis of prognostic factors in patients with brain metastases affecting survival
Variable | Present status | Chi-square | p-value | |||
---|---|---|---|---|---|---|
Alive | Dead | Lost to follow-up | ||||
Age (in years) | 18–30 | 1 | 0 | 3 | 7.747 | .654 |
31–40 | 0 | 2 | 5 | |||
41–50 | 4 | 15 | 19 | |||
51–60 | 2 | 17 | 16 | |||
61–70 | 2 | 11 | 12 | |||
>70 | 0 | 2 | 5 | |||
Gender | Male | 2 | 34 | 35 | 8.423 | .015* |
Female | 7 | 13 | 25 | |||
Histopathology | SCLC | 0 | 12 | 8 | 5.945 | .429 |
Adeno | 4 | 14 | 23 | |||
Squamous | 1 | 9 | 11 | |||
Others | 4 | 12 | 18 | |||
Extracranial metastases | Liver | 1 | 3 | 5 | 2.409 | .966 |
Bone | 2 | 11 | 18 | |||
Adrenal | 1 | 2 | 2 | |||
Multiple | 3 | 22 | 24 | |||
None | 2 | 9 | 11 | |||
Clinical presentation of brain Mets | Headache | 4 | 26 | 34 | 5.618 | .467 |
Seizure | 1 | 3 | 11 | |||
Weakness | 3 | 14 | 13 | |||
Asymptomatic | 1 | 4 | 2 | |||
RPA | I | 7 | 20 | 24 | 9.353 | .05* |
II | 0 | 3 | 12 | |||
III | 2 | 24 | 24 | |||
Number | Single | 2 | 13 | 15 | 0.165 | .921 |
Multiple | 7 | 34 | 45 | |||
Location | Cerebrum | 4 | 23 | 23 | 3.544 | .738 |
Cerebellum | 0 | 2 | 4 | |||
Multiple | 5 | 22 | 31 | |||
Synchronous/metachronous | Synchronous | 1 | 16 | 26 | 3.793 | .03* |
Metachronous | 8 | 31 | 34 | |||
RT | WBRT | 8 | 41 | 55 | 2.716 | .844 |
WBRT+ Boost | 0 | 2 | 1 | |||
SRS | 1 | 3 | 4 | |||
SRT | 0 | 1 | 0 |