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Table 2 Demographic and oncologic features of UTUC and UBC

From: Evaluation of molecular signatures in the urinary bladder and upper tract urothelial carcinomas: a prospective controlled clinical study

 

UTUC

UBC

p-value

Age, years (mean ± SD)

63.89 ± 10.21

61.9 ± 10.64

0.517

BMI (mean ± SD)

29.17 ± 6.5

30.97 ± 7.63

0.396

Gender, no. (%)

 Male

16 (84.2%)

25 (80.6%)

0.750

 Female

3 (15.8%)

6 (19.4%)

 

Comorbidities, no. (%)

Liver disease

 Yes

0

4 (12.9%)

0.103

 No

19 (100%)

27 (87.1%)

 

Diabetes mellitus

 Yes

2 (10.5%)

10 (32.3%)

0.081

 No

17 (89.5%)

21 (67.7%)

 

CKD

 Yes

1 (5.3%)

3 (9.7%)

0.577

 No

18 (94.7%)

28 (90.3%)

 

Serum creatinine, mg/dL (mean ± SD)

1.31 ± 0.5

1.3 ± 1.2

0.994

T stage, no. (%)

 T1

17 (89.5%)

7 (22.6%)

< 0.001*

 T2

1 (5.3%)

8 (25.8)

 

 T3

1 (5.3%)

13 (41.9)

 

 T4

0

3 (9.7%)

 

N stage, no. (%)

 N0/×

16 (84.2%)

18 (58.1%)

0.107

 N1 (single)

3 (15.8%)

5 (16.1%)

 

 N2 (multiple)

0

6 (19.4%)

 

 N3

0

2 (6.5%)

 

Organ confined, no. (%) (T stage ≤ 2, N0/×)

16 (84.2%)

12 (38.7%)

0.002*

Non-organ confined, no. (%) (T stage > 2, N0/×/+)

3 (15.8%)

19 (61.3%)

 

Cell type final pathology, no. (%)

 Pure TCC

19 (100%)

21 (67.7%)

0.105

 TCC with squamous differentiation

0

7 (22.6%)

 

 TCC with micropapillary component

0

1 (3.2%)

 

 TCC with sarcomatoid differentiation

0

1 (3.2%)

 

 TCC with squamous and sarcomatoid differentiation

0

1 (3.2%)

 

Grade,n(%)

 Low grade

0

1 (3.2%)

0.429

 High grade

19 (100%)

30 (96.8%)

 

Lymphovascular invasion final pathology, no. (%)

 Yes

14 (73.7%)

13 (41.9%)

0.029

 No

5 (26.3%)

18 (58.1%)

 
  1. *p ≤ 0.05