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Table 2 Patients’ characteristics and treatment outcome

From: Fifteen years’ experience of radiation therapy for resected advanced heterotopic ossification following motor vehicle accidents: outcome and side effects

Variable

No of patients (%)

Age (years)

13–47 (mean 27±8)

Sex

 Male

38 (97%)

 Female

1 (3%)

Cause of HO*

 Traumatic fracture

27 (69%)

 Brain injury

5 (13%)

 Spinal cord injury

4 (10%)

 Combined fracture and neurological injury

3 (8%)

Site

 Hip

35 (90%)

 Elbow

4 (10%)

Referral hospital

 Our hospital

22 (56%)

 Outside hospital

17 (44%)

Surgical resection

 Complete resection

3 (8%)

 Partial resection

36 (92%)

Type of Surgical resection

 Joint replacement

7 (18%)

 Surgical resection

32 (82%)

Radiotherapy given after

 1st resection

33 (85%)

 2nd resection

6 (15%)

Dose of radiotherapy

 700 cGy

34 (87%)

 800 cGy

5 (13%)

Testicular dose assessment

 Max calculated dose

81±83 cGy

 Mean calculated dose

33±44 cGy

 Measured dose (23 patients only)

58±40 cGy

Follow-up time (months)

24–144 (mean 74±33)

Time interval between trauma and surgery (months)

6–71 (mean 23±16)

Time interval between surgery and radiotherapy

 1 day

34 (87%)

 ≥ 2 days

5 (13%)

Median time to treatment failure (months)

3 (range 1–24)

Clinical status after treatment

 Regain full range of movement

18 (46%)

 Regain partial range of movement

20 (51%)

 No movement

1 (3%)

Clinical outcome at the time of the last follow-up

 No failure

33 (85%)

 Treatment failure

6 (15%)

Treatment outcome

 2y-TFFR**

87.2±5.4%

 8y-TFFR

79.3±9%

 5y-HOFFR***

97.2±3%

  1. HO* heterotopic ossification, TFFR** treatment failure-free rate, HOFFR*** heterotopic ossification failure-free rate