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Journal of the Egyptian National Cancer Institute
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  1. Vaginal metastasis should be kept in mind when evaluating the staging tests of all cancers, especially endometrial cancer.

    Authors: Mustafa Korkmaz, Melek Karakurt Eryılmaz, Ülkü Kerimoğlu, Mustafa Karaağaç, Aykut Demirkıran, Emine Türen Demir and Mehmet Artaç
    Citation: Journal of the Egyptian National Cancer Institute 2021 33:3
    Content type: Case Reports Published on:

  2. The number of people with implanted hip prosthesis has grown worldwide. For radiotherapy planning of patients with hip implants, few main challenges are encountered. The aim of the present study was to evaluat...

    Authors: Manindra Bhushan, Deepak Tripathi, Girigesh Yadav, Lalit Kumar, Rahul Lal Chowdhary, Anjali K. Pahuja, Tamilarasu Suresh, Sushil Kumar Shukla and Swarupa Mitra
    Citation: Journal of the Egyptian National Cancer Institute 2021 33:2
    Content type: Research Published on:

  3. Renal angiomyoadenomatous tumor (RAT) is a recently described rare renal neoplasm with variations in the presentation, gross, and microscopic findings, and having a benign course and good prognosis. It is char...

    Authors: Ankur Majumder, Ravi Hari Phulware, Arvind Ahuja, Anurag Singla and Pawan Kumar
    Citation: Journal of the Egyptian National Cancer Institute 2021 33:1
    Content type: Case Reports Published on:

  4. Urinary schistosomiasis and its severe complications, mainly bladder cancer, are scarce in non-endemic areas. The deficiency in knowledge and clinical experience of schistosomiasis may lead to inadequate manag...

    Authors: Mohamed S. Zaghloul, Tarek M. Zaghloul, Mai K. Bishr and Brian C. Baumann
    Citation: Journal of the Egyptian National Cancer Institute 2020 32:44
    Content type: Review Published on:

  5. Multiple myeloma (MM) is a human B cell neoplasia characterized by the clonal proliferation of malignant plasma cells in the bone marrow. Worldwide, hepatitis C virus (HCV) infection is a public health problem...

    Authors: Neemat M. Kassem, Hebatallah A. Kassem, Magdy Ibrahim, Hussam Zawam and Emad Hamada
    Citation: Journal of the Egyptian National Cancer Institute 2020 32:43
    Content type: Research Published on:

  6. Podophyllotoxin (PPT) is a naturally occurring compound obtained from the roots of Podophyllum species, indicated for a variety of malignant tumors such as breast, lung, and liver tumors. This toxic polyphenol...

    Authors: Popat S. Kumbhar, Asmita M. Sakate, Onkar B. Patil, Arehalli S. Manjappa and John I. Disouza
    Citation: Journal of the Egyptian National Cancer Institute 2020 32:42
    Content type: Research Published on:

  7. Endometrial carcinoma is one of the most common female cancers in developed countries. Disease stage is associated with the risk of disease relapse after radical treatment. Typically, the risk of disease relap...

    Authors: Leonardo Muratori, Paola Sperone, Gabriella Gorzegno, Anna La Salvia and Giorgio Vittorio Scagliotti
    Citation: Journal of the Egyptian National Cancer Institute 2020 32:41
    Content type: Case Reports Published on:

  8. To identify and report flaws of Internet-published articles in the Journal of the Egyptian National Cancer Institute (JENCI), Cairo University, through a retrospective documentary study on articles published duri...

    Authors: Sarah S. Nasr, Ghada M. Sherif, Amal S. Ibrahim and Rasha M. Allam
    Citation: Journal of the Egyptian National Cancer Institute 2020 32:39
    Content type: Research Published on:

  9. Primary malignant melanoma of the female urethra is an exceedingly rare tumor. It represents 0.2% of all malignant melanomas. Divergent differentiation towards non-melanocytic lineages has not been reported in...

    Authors: Tripti Nakra, Rohit Dadhwal, Rishi Nayyar, Sameer Rastogi, Aanchal Kakkar, Mehar Chand Sharma and Rajni Yadav
    Citation: Journal of the Egyptian National Cancer Institute 2020 32:40
    Content type: Case Reports Published on:

  10. Glutathione can reduce the oxidative stress by converting the unstable to stable molecules and its status in hepatocellular carcinoma (HCC) is correlated with tumor growth and metastasis.

    Authors: Shaimaa Gamal Hassan Elofey, Nevine F. Shafik, Noha Hassan Radwan, Osman Mohammed Mansour, Rasha Mahmoud Allam, Samia Shouman and Iman Attia AbdelGawad
    Citation: Journal of the Egyptian National Cancer Institute 2020 32:38
    Content type: Research Published on:

  12. The study investigated the expression and the clinicopathological significance of p53, p27, Ki-67, E-cadherin, and HER2 in upper urinary tract urothelial carcinomas (UTUC) from Tunisian patients. We performed ...

    Authors: Nabiha Missaoui, Ahlem Bdioui, Atika Baccouche, Oussema Belkacem, Wissem Hmida, Moncef Mokni and Sihem Hmissa
    Citation: Journal of the Egyptian National Cancer Institute 2020 32:36
    Content type: Research Published on:

  13. The challenging target in the workup of thyroid nodule(s) is to exclude or diagnose thyroid cancer efficiently prior to surgical intervention. The present work studied a panel of eight serum biomarkers to diff...

    Authors: Ragaa Abdelkader Ramadan, Wafaa Ragab, Ramy Samir Assaad, Ahmed Elsayed Shaaban and Amira Ibrahim Fayad
    Citation: Journal of the Egyptian National Cancer Institute 2020 32:35
    Content type: Research Published on:

  14. Telomere stability is one of the hallmarks of cancer that promotes cellular longevity, the accumulation of genetic alterations, and tumorigenesis. The loss of death domain-associated protein (DAXX) and α-thala...

    Authors: Marwa T. Hussien, Shimaa Shaban, Doaa F. Temerik, Shaaban R. Helal, Eman Mosad, Sahar Elgammal, Abeer Mostafa, Eman Hassan and Abeer Ibrahim
    Citation: Journal of the Egyptian National Cancer Institute 2020 32:34
    Content type: Research Published on:

  15. Wilms’ tumor (WT) represents about 6% of all childhood cancers. The overall survival markedly improved to exceed 90% in developed countries, yet some studies from developing counties still have poorer outcomes...

    Authors: Hosam Y. Asfour, Sahar A. Khalil, Al-Shimaa Zakaria, El-Sayed Ashraf and Wael Zekri
    Citation: Journal of the Egyptian National Cancer Institute 2020 32:32
    Content type: Research Published on:

  16. Absolute monocyte count (AMC) correlates with survival outcomes in various hematologic malignancies. However, its role in myeloid malignancies including AML needs to be highlighted. So, this prospective cohort...

    Authors: Ahmed Embaby, Ayman Fathy, Mohammad Al-Akkad, Ahmad Baraka, Taiseer Ibrahim, Nahla Zidan, Mohamed Refaat and Haitham Elsheikh
    Citation: Journal of the Egyptian National Cancer Institute 2020 32:33
    Content type: Research Published on:

  17. To evaluate the dosimetric impact of variable bladder filling on target and organ at risk (OARs) in cervical cancer patients undergoing chemoradiation. Forty consecutive patients with cervical cancer underwent...

    Authors: Soumya Dutta, Abhinav Dewan, Swarupa Mitra, Manoj Kumar Sharma, Sumeet Aggarwal, Soumitra Barik, M. Mahammood Suhail, Maninder Bhushan, Anurag Sharma, Inderjeet Kaur Wahi, Kiran Dobriyal and Jwala Mukhee
    Citation: Journal of the Egyptian National Cancer Institute 2020 32:31
    Content type: Research Published on:

  18. Colorectal carcinoma still represents a global health burden despite the advances in its management. The most common sites of distant metastasis from colorectal carcinoma are hepatic and pulmonary metastases w...

    Authors: Reham Alghandour, Gehad A. Saleh, Farida Ahmed Shokeir and Mohammad Zuhdy
    Citation: Journal of the Egyptian National Cancer Institute 2020 32:30
    Content type: Case Reports Published on:

  19. The phyllodes tumors are rare neoplastic disease which exhibits a benign behavior in adolescents female. After resection of a large benign breast tumor, insufficient breast contour may result with nipple areol...

    Authors: Mahmoud A. Hifny, Mohamed Yousef A., Asmaa Gaber R., Mohamed Abdelshafy Mohamed and Mahmoud Abdelhameid
    Citation: Journal of the Egyptian National Cancer Institute 2020 32:27
    Content type: Case Reports Published on:

  20. Postmastectomy lymphedema can be considered the main cause of upper extremity functional impairment in patients with breast cancer. Fatigue, pain, and limited range of motion are common symptoms. If left untre...

    Authors: Doaa Atef, Mohmed Maher Elkeblawy, Ashraf El-Sebaie and Walid Ahmed Ibrahim Abouelnaga
    Citation: Journal of the Egyptian National Cancer Institute 2020 32:29
    Content type: Research Published on:

  21. Allogeneic hematopoietic stem cell transplantation (Allo-HSCT) is a curative treatment for adult patients with acute lymphoblastic leukemia (ALL). Cyclophosphamide plus total body irradiation (TBI/Cy) or plus ...

    Authors: Mona Mahrous Abdelaty, Amr Gawaly, Gamal M. Fathy, Ibrahim Kabbash and Atef Taha
    Citation: Journal of the Egyptian National Cancer Institute 2020 32:28
    Content type: Research Published on:

  22. Inflammatory myofibroblastic tumor (IMT) is a mesenchymal tumor mainly found in lung or retroperitoneum and rarely affects head and neck region. Extensive English literature search reveals that less than fifty...

    Authors: Rituparna Biswas, Anirban Halder, Mimi Gangopadhyay and Dipanwita Biswas
    Citation: Journal of the Egyptian National Cancer Institute 2020 32:26
    Content type: Case Reports Published on:

  23. Adrenal tumors can be detected incidentally in 4 to 8% of patients radiologically. Adenomas, pheochromocytomas, and adrenocortical carcinomas represent the most common tumors of the adrenal glands. Rare histop...

    Authors: M. A. Elbaset, Mohamad H. Zahran, Mohamed Badawy, M. Abd Elhameed and Yasser Osman
    Citation: Journal of the Egyptian National Cancer Institute 2020 32:25
    Content type: Case Reports Published on:

  24. NME1 and KISS1 genes are two tumor metastasis suppressor genes, mapped to chromosomes 17q21.3 and 1q32 respectively. Here, we analyzed the association of EcoR1 (rs34214448—G/T) polymorphism in NME1 gene and 9 ...

    Authors: Sarah Antar, Naglaa Mokhtar, Mahmoud Adel Abd elghaffar and Amal K. Seleem
    Citation: Journal of the Egyptian National Cancer Institute 2020 32:24
    Content type: Research Published on:

  25. Central neurocytomas represent 0.25–0.5% of all intracranial tumors in adults. Leptomeningeal spread is uncommon, and the exact incidence of meningeal spread is unknown due to sparse literature. We present the...

    Authors: Shikha Goyal, Tejinder Kataria, Deepak Gupta, Aruj Dhyani, Ishani Mohapatra and Karanjit Singh Narang
    Citation: Journal of the Egyptian National Cancer Institute 2020 32:23
    Content type: Case Reports Published on:

  26. Transformation of low-grade follicular lymphoma to high-grade diffuse large B cell lymphoma (DLBCL) is known. However, the opposite is not commonly reported. In this report, we present a case of follicular lym...

    Authors: M. C. Suresh Babu, Antony George Francis Thottian, D. Lokanatha, Linu Abraham Jacob, K. N. Lokesh, A. H. Rudresha, L. K. Rajeev, Saldanha Smitha, Syed Adil Hassan, Khandare Pravin Ashok, C. S. Premalatha and M. N. Suma
    Citation: Journal of the Egyptian National Cancer Institute 2020 32:22
    Content type: Case Reports Published on:

  27. Wilms’ tumor (WT) affects one in 10,000 children and accounts for 5% of all childhood cancers. Although the overall relapse rate for children with WT has decreased to less than 15 %, the overall survival for p...

    Authors: Wael Zekri, Dalia M. Yacoub, Asmaa Ibrahim and Youssef Madney
    Citation: Journal of the Egyptian National Cancer Institute 2020 32:21
    Content type: Research Published on:

  28. The known efficacy of doxorubicin in metastatic breast cancer is countered by its dose-limiting myelosuppression and cardiotoxicity. Pegylated liposomal doxorubicin (PLD) was discovered to overcome these probl...

    Authors: Salah Mabrouk Khallaf, Jasmine Roshdy and Abeer Ibrahim
    Citation: Journal of the Egyptian National Cancer Institute 2020 32:20
    Content type: Research Published on:

  29. Wilms’ tumor (WT) is the most common renal malignant tumor of childhood. Metastatic WT has a worse prognosis than localized disease. This study aims to assess the clinical outcome and different prognostic fact...

    Authors: Moatasem Elayadi, Sarah Magdy, Ehab Khalil and Wael Zekri
    Citation: Journal of the Egyptian National Cancer Institute 2020 32:19
    Content type: Research Published on:

  30. Tumor-associated macrophages (TAM) are pivotal in remodeling of the tumor immune microenvironment and clinical outcome. Herein, we aim to evaluate the impact of immunohistochemical (IHC) expression of CD68 and...

    Authors: Mona Y. Y. Abd Allah, Maryan Waheeb Fahmi and Shaimaa EL-Ashwah
    Citation: Journal of the Egyptian National Cancer Institute 2020 32:18
    Content type: Research Published on:

  32. The focus of trastuzumab resistance biomarkers in recent decades has been on epigenetic and non-coding RNA-based mechanisms. In this study, the potential of miR-494 and its target genes as predictive biomarker...

    Authors: Adam Hermawan and Herwandhani Putri
    Citation: Journal of the Egyptian National Cancer Institute 2020 32:16
    Content type: Research Published on:

  33. Acute myeloid leukemia (AML) can modulate toll-like receptor-9 (TLR9) expression and activation. This study was conducted to elucidate the expression of TLR9 in AML patients and its relation to the prognosis o...

    Authors: Waiel M. A. Al-Kahiry, Enas A. M. Dammag, Hadeel S. T. Abdelsalam, Hayat K. Fadlallah and Mona S. Owais
    Citation: Journal of the Egyptian National Cancer Institute 2020 32:15
    Content type: Research Published on:

  35. The Oncotype DX is a quantitative assay of the expression of 16 tumor-related genes and 5 reference genes that predicts the potential of adjuvant chemotherapy benefit in estrogen receptor (ER)-positive early b...

    Authors: Salah Fayaz, Heba El-Sayed Eissa and Gerges Attia Demian
    Citation: Journal of the Egyptian National Cancer Institute 2020 32:13
    Content type: Research Published on:

  36. Squamous cell carcinoma of the oral cavity (OSCC) is the sixth most common malignancy. Surgery is mainstay treatment for oral cancers. Surgery in locally advanced OSCC presents many challenges primarily becaus...

    Authors: Diani Kartini, Akmal Taher, Sonar Soni Panigoro, Rianto Setiabudy, Sri Widia Jusman, Sofia Mubarika Haryana, Murdani Abdullah, Primariadewi Rustamadji, Denni Joko Purwanto, Noorwati Sutandyo, Indrati Suroyo, Budi Harapan Siregar, Haris Maruli and Saleha Sungkar
    Citation: Journal of the Egyptian National Cancer Institute 2020 32:12
    Content type: Research Published on:

  37. Hepatic complications are a well-known cause of both early and late mortality and morbidity in hematopoietic stem cell transplant (HSCT) recipients. Early diagnosis and management of hepatic complications is i...

    Authors: Haitham Abdelbary, Rasha Magdy, Mohammed Moussa and Inas Abdelmoaty
    Citation: Journal of the Egyptian National Cancer Institute 2020 32:11
    Content type: Research Published on:

  38. Laparoscopic gastrectomy has been used as a superior alternative to open gastrectomy for the treatment of early gastric cancer. However, the application of laparoscopic D2 lymphadenectomy remains controversial...

    Authors: Mohamed Aly Abdelhamed, Ahmed Abdellatif, Ahmed Touny, Ahmed Mostafa Mahmoud, Ihab Saad Ahmed, Sherif Maamoun and Mohamed Shalaby
    Citation: Journal of the Egyptian National Cancer Institute 2020 32:10
    Content type: Research Published on:

  39. Treatment for malignant embryonal brain tumors in young children usually employs cycles of standardly dosed cisplatinum followed by high-dose carboplatinum-containing conditioning with single or tandem autolog...

    Authors: Yasser Elborai, Mohammad Almutereen, Ossama M. Maher, Hanafy Hafez, Michelle A. Lee and Leslie Lehmann
    Citation: Journal of the Egyptian National Cancer Institute 2020 32:9
    Content type: Research Published on:

  40. Immune reconstitution inflammatory syndrome (IRIS) is a constellation of inflammatory disorders that are unmasked after the initiation of anti-retroviral therapy (ART) in Human immunodeficiency virus (HIV) inf...

    Authors: Mansi Mahajan, Bhanu Prasad Venkatesulu, Omar Sallam, Kanika Taneja, Megan Scott and Indira Brar
    Citation: Journal of the Egyptian National Cancer Institute 2020 32:8
    Content type: Case Reports Published on:

  41. Tumor-associated macrophages (TAMs) are important in regulating cross-talk between tumor cells and tumor microenvironment. TAMs are involved in multiple steps of tumor progression and invasion. This study aime...

    Authors: Shorouk E. Mwafy and Dina M. El-Guindy
    Citation: Journal of the Egyptian National Cancer Institute 2020 32:6
    Content type: Research Published on:

  42. Hashimoto thyroiditis (HT) is an autoimmune lymphocytic thyroiditis and is the most common form of thyroid inflammatory diseases. The association of HT with papillary thyroid carcinoma (PTC) has been described...

    Authors: Osama Hussein, Khaled Abdelwahab, Omar Hamdy, Shadi Awny, Nermin A. Megahed, Mohamed T. Hafez, Amr F. Elalfi, Mahmoud Abdelaziz, Khaled Gaballah and Mohamed Abdelkhalek
    Citation: Journal of the Egyptian National Cancer Institute 2020 32:7
    Content type: Research Published on:

  43. Worldwide, hepatocellular carcinoma (HCC) is a universal problem and its epidemiological data showed variation from place to place. Hepatocellular carcinoma (HCC) is the sixth and fourth common cancer in world...

    Authors: Wafaa M. Rashed, Mohamed Ahmed Mohamed Kandeil, Mohamed O. Mahmoud and Sameera Ezzat
    Citation: Journal of the Egyptian National Cancer Institute 2020 32:5
    Content type: Narrative Review Published on:

  44. This study aims to analyze risk factors, clinical profiles, treatment protocols, and disease outcomes in histologically proven resectable vulvar cancer (VC) patients according to tumor stage. This is a retrosp...

    Authors: Navin Kumar, Mukur Dipi Ray, D. N. Sharma, Rambha Pandey, Kanak Lata, Ashutosh Mishra, Durgesh Wankhede and Jyoutishman Saikia
    Citation: Journal of the Egyptian National Cancer Institute 2020 32:4
    Content type: Research Published on:

  45. The incidence of primary tracheal tumors is very low. Tracheal synovial sarcoma (SS) is even an extremely rare entity. Diagnosis of tracheal SS can be achieved with chromosomal translocation studies along with...

    Authors: Navin Kumar, Seema Kaushal, Kanaklata Kanaklata, Manoj Gowda and Sunil Kumar
    Citation: Journal of the Egyptian National Cancer Institute 2020 32:3
    Content type: Case Reports Published on:

  46. Radiation exposure from patients treated with radioactive iodine (131I) represents a radiation hazard to children and adolescents, representing the most vulnerable group of household contacts. Our aim was to calc...

    Authors: Khaled Salman, Shereen Wagieh, Aquib Bakhsh, Tarek Al-Monshy, Omnia Talaat, Musaed Al-Malki, Manal Al-Ezzi, Ashraf Fouda and Gihad Hamid
    Citation: Journal of the Egyptian National Cancer Institute 2020 32:2
    Content type: Research Published on:

  47. Ameloblastoma is the commonest odontogenic tumour of epithelial origin with a high incidence for developing local recurrence. We present a patient who developed local recurrence in both soft tissue and bone gr...

    Authors: Omar Hamdy, Sara Raafat, Gehad A. Saleh, Shadi Awny, Abdelhadi M. Shebl and Mohammed A. Hegazy
    Citation: Journal of the Egyptian National Cancer Institute 2020 32:1
    Content type: Case Reports Published on:

  48. Forkhead box A1 (FOXA1) plays an important role in several tumors. This study investigated the potential role of FOXA1 expression in thyroid tumors. We conducted a retrospective study of 110 thyroid lesions an...

    Authors: Nabiha Missaoui, Sameh Chouaibi, Sarra Limam, Nozha Mhamdi, Thouraya Zahmoul, Hajer Hamchi, Moncef Mokni and Sihem Hmissa
    Citation: Journal of the Egyptian National Cancer Institute 2019 31:11
    Content type: Research Published on:

  49. Plantago lanceolata L. is used in Iraqi folklore medicine to treat injuries, and its extract is prescribed by some herbalists for cancer patients. This research aimed to evaluate the effect of P. lanceolata leaf ...

    Authors: Khulood M. Alsaraf, Maeda H. Mohammad, Ahmed Majeed Al-Shammari and Ibrahim S. Abbas
    Citation: Journal of the Egyptian National Cancer Institute 2019 31:10
    Content type: Research Published on:

  50. Ovarian cancer represents a major global health burden that is rarely associated with distant metastasis. Axillary lymph node metastasis from ovarian cancer is rare and is reported only in few case reports in ...

    Authors: Mohammad Zuhdy, Reham Alghandour, Gena Abdelazeem, Gehad A. Saleh, Mahmoud M. Saleh, Mohamed Hamdy and Omar Hamdy
    Citation: Journal of the Egyptian National Cancer Institute 2019 31:9
    Content type: Case Reports Published on:
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  • ISSN: 2589-0409 (electronic)