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Table 1 Clinicopathologic and demographic characteristics of breast cancer patients and control groups

From: Association of polymorphisms in metastasis suppressor genes NME1 and KISS1 with breast cancer development and metastasis

 

Breast cancer patients (n = 75)

Control (n = 37)

P value

Age (years): median (IQR)

53 (41–64)

53 (38–63)

0.862

Menopausal status

 

Premenopausal

32 (42.7%)

20 (54.1%)

0.256

Postmenopausal

43 (57.3%)

17 (45.9%)

 

Tumor stage

 
 

Stage I

3 (4%)

  

Stage II

25 (33.3%)

  

Stage III

28 (37.3%)

  

Stage IV

19 (25.3%)

  

Node metastasis

 

Yes

52 (69.3%)

  

No

23 (30.7%)

  

Distant Metastasis

 

Yes

19 (25.3%)

  

No

56 (74.7%)

  

ER status

 

Positive

56 (74.7%)

  

Negative

18 (24%)

  

Unknown

1 (1.3%)

  

PR status

 

Positive

53 (70.7%)

  

Negative

21 (28%)

  

Unknown

1 (1.3%)

  

HER2 status

 

Positive

29 (38.7%)

  

Negative

37 (49.3%)

  

Unknown

9 (12%)

  

Ki-67

 

High

60 (80%)

  

Low

10 (13.3%)

  

Unknown

5 (6.7%)

  
  1. IQR interquartile range, P probability, n number, ER estrogen receptor, PR progesterone receptor, HER2 human epidermal growth factor receptor 2, Ki-67 cellular proliferation index
  2. Data are presented as count and percent except where otherwise noted. Tests used: Mann-Whitney U test for data presented as median (IQR) and chi-square test for data presented as count and percent