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  1. Multiple myeloma (MM) predominantly affects older patients; many of whom do not undergo autologous hematopoietic stem cell transplant (AHSCT) despite the associated survival benefits. This study was conceived ...

    Authors: Swaroop Revannasiddaiah, Prathap Raja Varma Muppalla Ayalgaraj Nagaraju, Rasmi Palassery, Apoorva Jagadish, Vinayak V. Maka, Nalini Kilara, Damiano Rondelli and Santhosh Kumar Devadas
    Citation: Journal of the Egyptian National Cancer Institute 2022 34:21
  2. Treatment-related toxicities in DLBCL (diffuse large B cell lymphoma) patients are higher in the initial phase of treatment (first cycle effect). Implementation of pre-phase treatment before definitive chemoth...

    Authors: A. H. Rudresha, Syed Adil Hassan, A. Sreevalli, D. Lokanatha, M. C. Suresh Babu, K. N. Lokesh, L. K. Rajeev, Smitha Saldanha, Antony G. F. Thottian, Kanika Sharma and Linu Abraham Jacob
    Citation: Journal of the Egyptian National Cancer Institute 2022 34:20
  3. Breast cancer is a fatal disease and a major reason of cancer associated death in females. Many factors along with miRNA are responsible for the development and the progression of the disease. The miRNA plays ...

    Authors: Apexa Raval, Jigna Joshi and Franky Shah
    Citation: Journal of the Egyptian National Cancer Institute 2022 34:19
  4. Vascular endothelial growth factor A (VEGF-A) plays an integral role in angiogenesis by contributing to growth, development, and metastasis of solid tumors. Recently, a single-nucleotide polymorphism +936C/T l...

    Authors: Sai Sushmitha Kontham, Charles Emmanuel Jebaraj Walter, Zioni Sangeetha Shankaran, Arvind Ramanathan, Nirmala Karuppasamy and Thanka Johnson
    Citation: Journal of the Egyptian National Cancer Institute 2022 34:18
  5. Repeated high-dose methotrexate (HDMTX) is a critical component of contemporary childhood acute lymphoblastic leukemia (ALL) treatment regimens. Serum albumin is considered a carrier of methotrexate (MTX) in t...

    Authors: Shaimaa Barakat, Hala Assem, Mostafa Salama, Neveen Mikhael and Yasmine El Chazli
    Citation: Journal of the Egyptian National Cancer Institute 2022 34:17
  6. Breast cancer (BC) is one of the most prevalent cancers in developing and developed countries among women worldwide. Mammography is one of the superior methods for BC detection, but it carries up to 20% false-...

    Authors: Mai Ali, Dina El Gayar, Normeen Hany, Abdel Hamid Ezzat and Reham Zeyada
    Citation: Journal of the Egyptian National Cancer Institute 2022 34:16
  7. Hepatic resection (HR) for hepatocellular carcinoma (HCC) is safe with good perioperative and long-term oncologic outcomes. There is a paucity of data with regards to intermediate-term outcomes (i.e., beyond 9...

    Authors: Sanaa Sheriff, Sudharsan Madhavan, Geraldine Yanlei Lei, Yiong Huak Chan, Sameer P. Junnarkar, Cheong Wei Huey, Jee Keem Low and Vishal G. Shelat
    Citation: Journal of the Egyptian National Cancer Institute 2022 34:14
  8. Despite antitumor properties, chemotherapy medication can create conditions in tumor cells that work in favor of the tumor. Doxorubicin, commonly prescribed chemotherapy agents, can increase the risk of migrat...

    Authors: Parisa Malakouti, Mobin Mohammadi, Mohammad Amin Boshagh, Abbasali Amini, Mohammad Ali Rezaee and Mohammad Reza Rahmani
    Citation: Journal of the Egyptian National Cancer Institute 2022 34:13
  9. Multimodality is the standard of care in gastric cancer but surgery remains the mainstay of curative treatment. As we are heading towards a more conservative approach for functional preservation without compro...

    Authors: Sangram K. Panda, Pradyumna K. Sahoo, Sunil K. Agarwala, Tim Houghton T, Prathamesh Panchakshari Chandrapattan, Vikas Sankar K and Ramkishan Nag
    Citation: Journal of the Egyptian National Cancer Institute 2022 34:12
  10. Stomach adenocarcinoma (STAD) dominates 80–90% of gastric cancer (GC). Over the years, it has been realized that the identification of the genes responsible for gastric carcinogenesis is essential to understan...

    Authors: Ranjan Jyoti Sarma, Sarathbabu Subbarayan, John Zohmingthanga, Saia Chenkual, Thomas Zomuana, Sailo Tlau Lalruatfela, Jeremy L. Pautu, Arindam Maitra and Nachimuthu Senthil Kumar
    Citation: Journal of the Egyptian National Cancer Institute 2022 34:11
  11. Waldenstrom macroglobulinemia (WM) is a rare lymphoma with an incidence rate of 3 per million people per year, with approximately 1000 to 1500 new cases diagnosed each year in the USA. It is primarily seen in ...

    Authors: Ahmed K. Awad, Merihan A. Elbadawy, Maty Boury, Amanda Rivera, Karam Motawea, Jaffer Shah, Shanli Parnia and Joseph Varney
    Citation: Journal of the Egyptian National Cancer Institute 2022 34:10
  12. Mucinous cystadenocarcinoma is a rare and recently described primary breast cancer with strikingly similar histomorphology to ovarian, pancreatic, and gastrointestinal counterparts. The diagnosis cannot be mad...

    Authors: Kanwalpreet Kaur, Ashini Shah, Jahnvi Gandhi and Priti Trivedi
    Citation: Journal of the Egyptian National Cancer Institute 2022 34:9
  13. Circulating tumor DNA (ctDNA) has become one of the crucial components for cancer detection with the increase of precision medicine practice. ctDNA has great potential as a blood-based biomarker for the detect...

    Authors: Sudeepto Saha, Yusha Araf and Salman Khan Promon
    Citation: Journal of the Egyptian National Cancer Institute 2022 34:8
  14. Adnexal masses are a common problem seen in women. The aim of this study was to determine the appropriate cut-off for symptom-based score to predict ovarian malignancy in women with adnexal mass and to evaluat...

    Authors: Amruthamshu Krishnamurthy, Jayalakshmi Durairaj and Murali Subbaiah
    Citation: Journal of the Egyptian National Cancer Institute 2022 34:7
  15. High-grade serous ovarian carcinoma (HGSOC) is classified into four molecular subtypes; mesenchymal, proliferative, immunoreactive, and differentiated, with suggested different prognosis. Addressing the presen...

    Authors: Marwa Khashaba, Mohamed Fawzy, Azza Abdel-Aziz, Ghada Eladawei and Reham Nagib
    Citation: Journal of the Egyptian National Cancer Institute 2022 34:6
  16. Lymphoepithelioma-like carcinoma (LELC) is an unusual histological malignancy type. Due to the rarity of this disease, we used the Surveillance, Epidemiology, and End Results (SEER) database to investigate com...

    Authors: Xiaoqian Zhai, Jiewei Liu, Donghao Lu and Qinghua Zhou
    Citation: Journal of the Egyptian National Cancer Institute 2022 34:5
  17. Ear keloids are abnormal continuously growing healing process following cutaneous injury. Surgical excision is the standard treatment strategy; however, 50–80% of cases develop recurrence. Adjuvant radiotherap...

    Authors: Reham Mohamed, Abosaleh Abosaleh Elawadi, Reham Al-Gendi, Safa Al-Mohsen, Shabeer Wani and Ahmed Wafa
    Citation: Journal of the Egyptian National Cancer Institute 2022 34:4
  18. Oral carcinoma cuniculatum (OCC) is an unacquainted well-differentiated subtype of oral squamous cell carcinoma, which displays unique clinic-pathological features. Up to date, OCC remains rare with about 75 r...

    Authors: Safaa Baz, Hatem Wael Amer and Ali A. Wahed
    Citation: Journal of the Egyptian National Cancer Institute 2022 34:3
  19. Breast conserving surgery (BCS) has been a standard procedure for the treatment of breast cancer instead of mastectomy whenever possible. Lateral chest wall perforator flaps are one of the volume replacement t...

    Authors: Ahmed Orabi, Mina M G Youssef, Tamer M. Manie, Mohamed Shaalan and Tarek Hashem
    Citation: Journal of the Egyptian National Cancer Institute 2022 34:2
  20. Postoperative chemoradiotherapy is recommended for patients with head and neck squamous cell carcinoma with positive margins or extracapsular extension at high risk of recurrence. However, high-dose radiothera...

    Authors: Wataru Makino, Joichi Heianna, Kazuki Ishikawa, Takeaki Kusada, Hitoshi Maemoto, Takuro Ariga, Akira Matayoshi, Toshiyuki Nakasone, Hitoshi Hirakawa, Shinya Agena, Yukashi Yamashita, Hiroyuki Maeda and Sadayuki Murayama
    Citation: Journal of the Egyptian National Cancer Institute 2021 33:40
  21. Pathological complete response (pCR) is a surrogate for the efficacy of neoadjuvant chemotherapy (NCT) in locally advanced breast cancer (LABC). We analyzed the predictive clinical factors for pathological res...

    Authors: Kyrillus S. Shohdy, Doaa S. Almeldin, Madonna A. Fekry, Mahmoud A. Ismail, Nedal A. AboElmaaref, Esraa G. ElSadany, Baher M. Hamza, Fatma H. El-Shorbagy, Ahmad S. Ali, Hanaa Attia and Loay Kassem
    Citation: Journal of the Egyptian National Cancer Institute 2021 33:39
  22. Abnormal expression patterns of microRNAs (miRs) play an important role in the development and progression of malignancy. Identification of the clinical significance and prognostic value of these small molecul...

    Authors: M. M. Khalifa, N. E. Zaki, A. A. Nazier, M. A. Moussa, R. Abdel Haleem, M. A. Rabie and A. R. Mansour
    Citation: Journal of the Egyptian National Cancer Institute 2021 33:37
  23. To determine locations, relative frequencies, imaging features, and pattern of distribution of extrahepatic metastasis from hepatocellular carcinoma (HCC) on 2-deoxy-2-[fluorine-18]fluoro-D-glucose (18F-FDG) PET ...

    Authors: Manjit Sarma, Subramanyam Padma, Parvathy Pavithran, Vijay Harish Somasundaram and Palanisamy Shanmuga Sundaram
    Citation: Journal of the Egyptian National Cancer Institute 2021 33:36
  24. Tumor eradication is one of the most important challengeable categories in oncological studies. In this account, besides the molecular genetics methods including cell therapy, gene therapy, immunotherapy, and ...

    Authors: Nafiseh Sobhani and Ali Akbar Samadani
    Citation: Journal of the Egyptian National Cancer Institute 2021 33:34
  25. The expression of hERG K+ channels is observed in various cancer cells including epithelial, neuronal, leukemic, and connective tissue. The role of hERG potassium channels in regulating the growth and death of ca...

    Authors: Vaishali M. Patil, Anand Gaurav, Priyanka Garg and Neeraj Masand
    Citation: Journal of the Egyptian National Cancer Institute 2021 33:33
  26. Cancer refers to a group of some of the worldwide most diagnosed and deadliest pathophysiological conditions that conquered researchers’ attention for decades and yet begs for more questions for a full compreh...

    Authors: Ibrahim Diori Karidio and Senay Hamarat Sanlier
    Citation: Journal of the Egyptian National Cancer Institute 2021 33:32
  27. Glioma is one of the most malignant brain tumors, accounting for about half of the gliomas that occur in central nervous system (CNS), originates from the glial tissue of the brain. The aim of the present stud...

    Authors: Abdol Ali Ebrahimi, Hasan Ashoori, Farnaz Vahidian, Iman Samiei Mosleh and Shaghayegh Kamian
    Citation: Journal of the Egyptian National Cancer Institute 2021 33:31
  28. Squamous cell carcinoma of the esophagus ranks as the most common cause of cancer incidence and mortality in males and the second most common in females. Surgery alone is associated with poor long-term surviva...

    Authors: Partha Sarathi Roy, Gaurav Kumar, Sreya Mallik, Satya Sadhan Sarangi, Bhargab Jyoti Saikia, Munlima Hazarika and Abhijit Talukdar
    Citation: Journal of the Egyptian National Cancer Institute 2021 33:35
  29. Brown tumors are benign osteoclastic bone lesions encountered in patients with hyperparathyroidism. These tumors may demonstrate aggressive, destructive features in the skeleton and imitate metastatic bone les...

    Authors: Ula Al-Rasheed, Fareed Barakat and Akram Al-Ibraheem
    Citation: Journal of the Egyptian National Cancer Institute 2021 33:30
  30. Cancer is one of the leading causes of death worldwide. According to GLOBOCAN estimates, there were 341,831 deaths from cervical cancer in 185 countries in 2020. The aim of this study was to compare equieffect...

    Authors: Osman Vefa Gul, Gokcen Inan and Hamit Basaran
    Citation: Journal of the Egyptian National Cancer Institute 2021 33:28
  31. On account of extremity wide range of movements and difficulty of reproducibility during irradiation of extremity sarcomas, assorted immobilization strategies are employed to eliminate setup errors. The study ...

    Authors: Reham Mohamed, Muhammad Shuja, Asaad Al-Hazienh and Moamen Aly
    Citation: Journal of the Egyptian National Cancer Institute 2021 33:27
  32. The survival of pineoblastoma patients is low, particularly in infants and those with metastatic disease. This study aimed to analyze the prognostic factors affecting the outcome of Pineoblastoma in different ...

    Authors: Ahmed Elhemaly, Mohamed S. Zaghloul, Soha Ahmed, Hala Taha, Amal Refaat, Eslam Maher, Mohamed El-Beltagy and Wael Zekry
    Citation: Journal of the Egyptian National Cancer Institute 2021 33:26
  33. Diffuse large B cell lymphoma (DLBCL) can occur at nodal and/or extra-nodal sites. After the gastrointestinal tract, cutaneous involvement predominates in extra-nodal DLBCL. Skin involvement at presentation ca...

    Authors: Sindhu Kilaru, Soumya Surath Panda, Sourav Mishra, Debahuti Mohapatra, Manas Baisakh, Spoorthy Kolluri, Suma Devaraj, Lalatendu Moharana and Ghanashyam Biswas
    Citation: Journal of the Egyptian National Cancer Institute 2021 33:25
  34. Telomere dysfunction is one of the hallmarks of cancer and is crucial to prostate carcinogenesis. TERF1 is a gene essential to telomere maintenance, and its dysfunction has already been associates with several...

    Authors: Gabriel Arantes dos Santos, Nayara Izabel Viana, Ruan Pimenta, Vanessa Ribeiro Guimarães, Juliana Alves de Camargo, Poliana Romão, Sabrina T. Reis, Katia Ramos Moreira Leite and Miguel Srougi
    Citation: Journal of the Egyptian National Cancer Institute 2021 33:24
  35. Glufosfamide (β-d-glucosylisophosphoramide mustard, GLU) is an alkylating cytotoxic agent in which ifosforamide mustard (IPM) is glycosidically linked to the β-d-glucose molecule. GLU exerted its cytotoxic effect...

    Authors: Doaa E. Ahmed, Fatma B. Rashidi, Heba K. Abdelhakim, Amr S. Mohamed and Hossam M. M. Arafa
    Citation: Journal of the Egyptian National Cancer Institute 2021 33:22
  36. Hodgkin lymphoma (HL) is lymphoid neoplasm usually affecting lymphatic system; it accounts 3.6% of cancers in Saudi Arabia. Modern treatment protocols had shown particular success rates in overall-survival (OS...

    Authors: Nawaf Alkhayat, Mohammad Alshahrani, Ghaleb Elyamany, Qanita Sedick, Walid Ibrahim, Hasna Hamzi, Amal Binhassan, Mohamed Othman, Saeed Alshieban, Mansour S. Aljabry, Shuaa Asiri, Muneerah Alzouman, Omar Alsuhaibani, Fahad Alabbas, Omar Alsharif and Yasser Elborai
    Citation: Journal of the Egyptian National Cancer Institute 2021 33:21
  37. Globally, head and neck cancer is the sixth most common cancer. Despite the advancement in treatment, drug resistance remains a major cause for setback. In an earlier work, the authors reported that Boswellia dal...

    Authors: Akinbobola Peace Otitoju, Ishaya Yohanna Longdet, Taiwo Emmanuel Alemika and Vikram Prakash Gota
    Citation: Journal of the Egyptian National Cancer Institute 2021 33:20
  38. The poor outcomes from triple-negative breast cancer (TNBC) therapy are mainly because of TNBC cells’ heterogeneity, and chemotherapy is the current approach in TNBC treatment. A previous study reported that C...

    Authors: Dhania Novitasari, Riris Istighfari Jenie, Jun-ya Kato and Edy Meiyanto
    Citation: Journal of the Egyptian National Cancer Institute 2021 33:19
  39. Gastrointestinal complications are not uncommon in patients of Acute Leukemia. Intussusception as a complication in leukemia, although described, is exceedingly rare. Also, it is usually seen after chemotherap...

    Authors: Ankur Majumder, Sunayana Misra, Vijay Kumar and Shilpa Khanna Arora
    Citation: Journal of the Egyptian National Cancer Institute 2021 33:18
  40. Administration of green tea (GT) catechins has been reported to ensue antitumor activity in combination with chemotherapeutic drugs against different cancer types. Irinotecan (IRN) is a highly effective chemot...

    Authors: Gaurab Borah and Manuj Kumar Bharali
    Citation: Journal of the Egyptian National Cancer Institute 2021 33:17
  41. P D-L1 is expressed in tumor cells and plays a crucial role in tumor immune escape. Tumor-infiltrating lymphocytes (TILs) as CD8 T cells contribute to reduced tumor growth. Few studies investigated the prognos...

    Authors: Mayada Saad Farrag, Khaled Abdelwahab, Nesrine Saad Farrag, Waleed Elsayed Elrefaie and Ziad Emarah
    Citation: Journal of the Egyptian National Cancer Institute 2021 33:16
  42. Angiogenesis is the formation of new vascular networks from preexisting ones through the migration and proliferation of differentiated endothelial cells. Available evidence suggests that while antiangiogenic t...

    Authors: Ayodipupo S. Oguntade, Faez Al-Amodi, Abdullah Alrumayh, Muath Alobaida and Mwango Bwalya
    Citation: Journal of the Egyptian National Cancer Institute 2021 33:15
  43. Aberrant T cell antigen expression has been well documented in diffuse large B cell lymphomas. However, co-expression of multiple T cell antigens including CD3, which has been considered a specific marker for ...

    Authors: Anurag Mehta, Prerna Chadha, Poojan Agarwal and Sunil Pasricha
    Citation: Journal of the Egyptian National Cancer Institute 2021 33:14
  44. The burden of cancer in Sri Lanka is on the rise. The overall incidence of cancer in Sri Lanka has doubled over the past 25 years with a parallel rise in cancer-related mortality. Cancer has become the second ...

    Authors: Umesh Jayarajah and Anuruddha M. Abeygunasekera
    Citation: Journal of the Egyptian National Cancer Institute 2021 33:13
  45. Acute oral mucositis has been infrequently studied in the patients with head and neck squamous cell carcinoma (HNSCC) receiving once-weekly cisplatin-based chemoradiotherapy (CRT). Hence, this analysis was con...

    Authors: Vanita Noronha, Vijay M. Patil, Gunjesh Kumar Singh, Amit Joshi, Nandini Menon, Sarbani Ghosh Lashkar, Vijayalakshmi Mathrudev, Kavita Nawale Satam and Kumar Prabhash
    Citation: Journal of the Egyptian National Cancer Institute 2021 33:12

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