Identification of serum biomarker panel to differentiate malignant from benign thyroid nodules using multiplex bead assay

Journal of the Egyptian National Cancer Institute

Table 1 Comparison of sex and age between the studied groups

	Control (n = 20)	BTN (n = 20)	MTN (n = 20)	H	p
Sex (male to female)	16:4	18:2	16:4	1.035	0.750
Age (years)
Mean ± SD	40.9 ± 11.9	45.95 ± 12.45	44.6 ± 12.96	0.883	0.419
Min.–Max	18–59	18–68	16–72
Median	43	45.5	45
Median	p₁ = 0.876, p₂ = 0.893, p₃ = 0.745

BTN benign thyroid nodule, MTN malignant thyroid nodule
H, p: H and p values for Kruskal-Wallis test, Significance between groups (Sig. bet. gps) was done using post hoc test (Dunn’s multiple comparisons test)
p₁: p value for comparing between control and BTN
p₂: p value for comparing between control and MTN
p₃: p value for comparing between BTN and MTN
*Statistically significant at p ≤ 0.05