Table 6 Comparison of some laboratory markers according to GSTP1 genotype
From: Relation between GSTP1 polymorphism and oxidative stress in patients with hepatocellular carcinoma
Heterozygous variant | Homozygous variant | Wild | p value | |
|---|---|---|---|---|
Median (range) | Median (range) | Median (range) | ||
ALT (U/L) (up to 45) | 51.0 (23-135) a | 106.50 (54-181) b | 43.50 (9-150) c | 0.049* |
ALB (g/dl) (3.5:5.2) | 3.30 (1.8-4.87) | 3.1 (2.7-4.2) | 3.1 (2.2-4.3) | 0.579 |
PLT*10^9/L (150-400) | 101.5 (50-260) | 102.5 (63-244) | 120.000 (28-365) | 0.422 |
AST (U/L) (up to 41) | 79 (19.8-208) | 69.5 (30-229) | 73 (10-508) | 0.698 |
BIL (mg/dl) (up to 1.1) | 1.2 (0.7-3.82) | 1.3 (0.2-5.8) | 1.2 (0.5-4.9) | 0.684 |
ALP (U/L) (up to 279) | 165 (70-713) | 207.0 (85-900) | 150.0 (57-808) | 0.543 |
INR (up to 1) | 1.21 (1-2.5) | 1.2 (1.00-1.31) | 1.2 (1-1.8) | 0.486 |
Creatinine (mg/dl) (0.7-1.4) | 0.9 (0.6-1.5) | 1 (0.80-1.2) | 0.9 (0.5-1.84) | 0.835 |
UREA (mg/dl) (15-45) | 30 (17-60) | 32 (19-50) | 32 (17-71) | 0.363 |
AFP (ng/ml) (up to 10.5) | 103.4 (4.938295) | 580.8 (2.3-155449) | 165 (2.3-126817) | 0.144 |
LDH (U/L) (up to 250) | 190 (88-331) | 209.5 (101-330) | 206 (105-303) | 0.012* |
HB (gm/dl) N: Male (13:18) Female (12:16) | 12.4 (8.2-15.7) | 11.4 (9.3-14.8) | 12.5 (8.9-15.9) | 0.835 |
TLC*10^9/L (4.0:11.0) | 4.7 (2.5-13.9) | 4.6 (2.5-10.065) | 4.8 (10.2-12.87) | 0.683 |
GSH (μM/mg) (684-2525) | 2000 (877-2911) | 1507.5 (894-2241) | 1851 (862-3011) | 0.208 |
PC (%) | 0.8 (0.4-79.5) | 0.8 (0.7-1) | 0.8 (0.5-67.5) | 0.867 |