Table 1 Risk factors for HCC development

1- Infectious

a)- HBV

b)- HCV

1- Host-related risk factors

a)- Gender

b)- Ethnicity

c)- Obesity

d)- Diet

e)- Oral contraceptives (OCs)

f)- Autoimmune Hepatitis

(Cryptogenic cirrhosis)

g)- Diabetes Mellitus

h)- NAFLD

2- Non-infectious

a) Chemical compounds

b) Alcohol abuse

c) Smoking tobacco

2- Genetic-related risk factors

i)- Monogenic risk factors:

a)- Alpha 1 antitrypsin deficiency

b)- Hemochromatosis

ii)- polygenic risk factors:

a)- Family history

b)- Aflatoxins