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Journal of the Egyptian National Cancer Institute
Fig. 3 | Journal of the Egyptian National Cancer Institute

Fig. 3

From: Unmasking lymphoma immune reconstitution inflammatory syndrome in a patient with pyrexia of unknown origin: a case report

Fig. 3

Sections demonstrate atypical nodular lymphoid infiltrate separated by ill-defined fibrotic bands. The nodular lymphoid infiltrate is mainly composed of large atypical cells morphologically resembling Reed-Sternberg cells, in a mixed inflammatory background consisting of small lymphocytes, histiocytes, plasma cells, and occasional eosinophils. The large atypical cells are positive for CD30, PAX5 (dim) and negative for CD20, CD15, CD45, and CD3. CD3 stains numerous T cells in the background. EBER-ish is positive in the Hodgkin cells based on EBV stain performed on with appropriate controls

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