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Table 3 Etiology of liver injury and abnormal liver function test

From: Liver disease during and after hematopoietic stem cell transplantation in adults: a single-center Egyptian experience

Variable 
Abnormal pre-transplant liver functionGrade I
Grade II
Grade III
Grade IV
14 (7.4%)
7 (3.7%)
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Abnormal liver function during transplantGrade I
Grade II
Grade III
Grade IV
53 (27.9%)
15 (7.9%)
12 (6.3%)
12 (6.3%)
Abnormal liver function post-transplantGrade I
Grade II
Grade III
Grade IV
44(23.2%)
15 (7.9%)
5 (2.6%)
10 (5.3%)
Classification of liver injury in allogeneic patients from D0 to Day + 100Drugs/conditioning regimen
Acute GVHD
Flare of viral hepatitis
Sepsis
SOS
CMV hepatitis
39(38.2%)
15(14.7%)
2 (2%)
2 (2%)
2 (2%)
2 (2%)
Classification of liver injury in allogeneic patients after day + 100Chronic GVHD
Double pathology
Drugs/conditioning regimen
Flare of viral hepatitis
Iron overload
Sepsis
36(35.3%)
12(11.8%)
4 (3.9%)
2 (1%)
3 (2.9%)
2 (2%)
Classification of liver injury in autologous patients in the early post-transplant periodDrugs/conditioning regimen
Flare of viral hepatitis
Sepsis
53(27.9%)
15 (7.9%)
12 (6.3%)
Classification of liver injury in autologous patients in the late post-transplant periodDrugs/conditioning regimen
Flare of viral hepatitis
Sepsis
10(11.4%)
1 (1.1%)
1 (1.1%)