Liver disease during and after hematopoietic stem cell transplantation in adults: a single-center Egyptian experience

Journal of the Egyptian National Cancer Institute

Table 3 Etiology of liver injury and abnormal liver function test

Variable
Abnormal pre-transplant liver function	Grade I Grade II Grade III Grade IV	14 (7.4%) 7 (3.7%) ------- ------
Abnormal liver function during transplant	Grade I Grade II Grade III Grade IV	53 (27.9%) 15 (7.9%) 12 (6.3%) 12 (6.3%)
Abnormal liver function post-transplant	Grade I Grade II Grade III Grade IV	44(23.2%) 15 (7.9%) 5 (2.6%) 10 (5.3%)
Classification of liver injury in allogeneic patients from D0 to Day + 100	Drugs/conditioning regimen Acute GVHD Flare of viral hepatitis Sepsis SOS CMV hepatitis	39(38.2%) 15(14.7%) 2 (2%) 2 (2%) 2 (2%) 2 (2%)
Classification of liver injury in allogeneic patients after day + 100	Chronic GVHD Double pathology Drugs/conditioning regimen Flare of viral hepatitis Iron overload Sepsis	36(35.3%) 12(11.8%) 4 (3.9%) 2 (1%) 3 (2.9%) 2 (2%)
Classification of liver injury in autologous patients in the early post-transplant period	Drugs/conditioning regimen Flare of viral hepatitis Sepsis	53(27.9%) 15 (7.9%) 12 (6.3%)
Classification of liver injury in autologous patients in the late post-transplant period	Drugs/conditioning regimen Flare of viral hepatitis Sepsis	10(11.4%) 1 (1.1%) 1 (1.1%)