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Table 1 Characteristics of breast cancer patients

From: Detection of activating mutations in liquid biopsy of Egyptian breast cancer patients using targeted next-generation sequencing: a pilot study

Patient’s characteristics

Total No. = 8

No. (%)

Age (years)

 Mean ± SD

40 ± 7.01

 Median

41

 Range

29-48

Stage at diagnosis

 II

2/8 (25%)

 III

5/8 (62.5%)

 IV

1/8 (12.5%)

Immunohistochemistry

ER status

 Positive

5/8 (62.5%)

 Negative

3/8 (37.5%)

PR status

 Positive

4/8 (50%)

 Negative

4/8 (50%)

HER2 neu

 Positive

1/8 (12.5%)

 Negative

7/8 (87.5%)

KI 67

 High

4/8 (50%)

 Low

1/8 (12.5%)

 Unknown

3/8 (37.5%)

Molecular subtype

 Luminal A

1/8 (12.5%)

 Luminal B

4/8 (50%)

 Triple negative disease

3/8 (37.5%)

Metastasis

 Metastatic:

6/8 (75%)

 Liver

4/6 (66.7%)

 Bone

3/6 (50%)

 Lung

4/6 (66.7%)

 Brain

0

 Local recurrence

1/6 (16.7%)

 Early disease, non metastatic:

2/8 (25%)

Microsatellite instability (MSI) status

 Microsatellite stable (MSS)

2/8 (25%)

 Microsatellite instability-low (MSI-L)

3/8 (37.5%)

 Microsatellite instability-high (MSI-HI)

3/8 (37.5%)