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Table 2 Salvage treatment and outcome of all refractory/relapsed patients

From: Clinicopathologic features and therapy outcome in childhood Hodgkin’s lymphoma: a report from tertiary care center in Saudi Arabia

# of patient

Second line of chemotherapy

HSCT

Response

Outcome

Refractory patients

1

ICE

Yes

RD

Died from disease

2

ESHAP/brentuximab vedotin

Yes

CR2

Alive in CR

3

ICE

Yes

CR2

Alive in CR

4

ESHAP/brentuximab vedotin

Yes

CR2

Alive in CR

5

ICE

No

RD

Died from disease

6

ICE then ESHAP/brentuximab vedotin

No

RD

Alive with disease

7

ICE

Yes

CR2

Alive in CR

8

ICE then ESHAP/brentuximab vedotin

Yes

CR2

Alive in CR

Relapsed patients

1

ICE then gemcitabine/brentuximab vedotin

No

RD

Died from disease

2

ICE

No

CR2

Alive in CR

3

ICE

No

CR2

Alive in CR

4

ICE

No

CR2

Alive in CR

5

ICE

Yes

CR2

Alive in CR

6

ICE

Yes

CR2

Alive in CR

7

ESHAP/brentuximab vedotin

Yes

CR2

Alive in CR

8

ICE

Yes

CR2

Alive in CR

9

Refused treatment

No

RD

Alive with disease

10

ICE then gemcitabine/brentuximab vedotin

Yes

CR2

Alive in CR

11

ESHAP/brentuximab vedotin

Yes

CR2

Alive with 2ry neoplasm

  1. ICE ifosfamide/carboplatin/etoposide, ESHAP etoposide/solu-medrol/high dose ara-c/platinum-cisplatin, HSCT hematopoietic stem cell transplant, CR2 second complete remission, CR complete remission, RD refractory disease