Time period | Control | Glufosfamide (µM)1 |
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10 | 25 | 50 |
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48 h | 4.0 ± 0.2a | 15.1a ± 1.3 | 22.5a ± 1.2 | 54.5a ± 2.5 |
72 h | 4.2 ± 0.5b | 23.13*,b ± 1.9 | 35.0*,b ± 2.3 | 72.5*,b ± 4.1 |
- Data represent mean ± SE, n = 3
- 1Glufosfamide was used in its IC50 value beside two of its fractions; 10 and 25 µM
- The number of HepG2 cells used was in the range of 5 × 105 ~ 5 × 106 cells/mL
- Caspase-9 content was expressed as ng/mL
- *Significantly different from the same concentration incubated with HepG2 cells for 48 h at P < 0.05, using independent Student’s t test
- a,bData in the same rows having the same superscript are significantly different from each other at P < 0.05 using one way analysis of variance (ANOVA) followed by Tukey as post hoc test