Time period | Control | Ifosfamide (µM)1 |
|---|
25 | 50 | 100 |
|---|
48 h | 20.9 ± 1.2 | 19.3 ± 0.9 | 15.2a ± 0.4 | 11.6a ± 0.5 |
72 h | | 16.2*,b ± 0.5 | 12.1*,b ± 0.3 | 8.5*,b ± 0.4 |
- Data represent mean ± SE (n = 4)
- ATP level is expressed as nmol/mg protein
- 1Ifosfamide was used in its IC50 value beside two of its fractions; 25 and 50 µM
- The number of HepG2 cells used was in the range of 5 × 105 ~ 5 × 106 cells/mL
- *Significantly different from the same concentration incubated with HepG2 cells for 48 h at P < 0.05, using independent Student’s t test
- a,bData in the same rows having the same superscript are significantly different from each other at P < 0.05 using one-way analysis of variance (ANOVA) followed by Tukey as post hoc test
