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Table 4 Simple and multiple logistic regression analysis of predictors of pathologic complete response (pCR)

From: Pathological responses and survival outcomes in patients with locally advanced breast cancer after neoadjuvant chemotherapy: a single-institute experience

 

Odds ratio

p-value

95% confidence interval

pCR (simple regression)

 Age group (≤ 50 vs. > 50)

1.09

0.79

0.57

2.08

 cT1, 2 vs. cT3, 4

0.40

0.017

0.18

0.85

 N0 vs. N+

0.48

0.116

0.20

1.20

 HR (positive)

0.74

0.378

0.38

1.44

 HER2 (positive)

1.21

0.624

0.57

2.58

 Optimal chemotherapy (yes)

3.05

0.018

1.22

7.64

 KI-67 (high)

2.25

0.056

0.98

5.19

pCR (multiple regression)

 Age group (≤ 50 vs. > 50)*

1.09

0.854

0.43

2.77

 cT1, 2 vs. cT3, 4*

0.28

0.008

0.11

0.71

 N0 vs. N+*

0.59

0.4

0.17

2.01

 HR (positive)*

0.69

0.435

0.27

1.78

 Optimal chemotherapy (yes)*

1.49

0.016

1.08

2.06

  1. *These variables were included in the same multiple logistic regression model