Table 6 Simple and multiple Cox regression analyses of predictors of distant metastasis-free survival (DMFS)

 Age group (≤ 50 vs. > 50)

0.70

0.113

0.46

1.09

 HR (positive)

0.65

0.065

0.41

1.03

 cT1, 2 vs. c T3, 4

0.74

0.372

0.39

1.43

 N0 vs. N+

2.47

0.218

0.58

10.47

 ORR (yes)

0.33

0.02

0.13

0.84

 PCR (yes)

0.34

0.021

0.14

0.85

 HER2 (positive)

0.89

0.727

0.45

1.75

 Optimal chemotherapy (yes)

0.58

0.024

0.36

0.93

 Age group (≤ 50 vs. > 50)*

0.45

0.012

0.24

0.84

 HR (positive)*

0.51

0.022

0.29

0.91

 pCR (yes)*

0.34

0.044

0.12

0.97

 Optimal chemotherapy (yes)*

0.51

0.027

0.28

0.93