Table 4 Summary of the association between VEGF-A +936C/T polymorphism and CRC in different genetic models and according to ethnicity

C vs. T

Overall

0.9983

[0.91–1.09]

0.97169

0.0007

0.6458

0.6927

East Asian

0.6537

[0.53–0.80]

0.00003

0.4693

0

0.0177

South Asian

1.3375

[0.84–2.11]

0.2141

NA

NA

NA

Caucasian

1.0563

[0.91–1.22]

0.4637

0.1745

0.3493

0.6018

Quality of the study

1.2242

[0.78–1.90]

0.3694

NA

NA

NA

CC vs. CT + TT

Overall

1.0221

[0.92–1.13]

0.68371

0.0004

0.6591

0.6999

East Asian

0.6273

[0.49–0.78]

0.00006

0.4845

0

0.1031

South Asian

1.2901

[0.78–2.12]

0.3191

NA

NA

NA

Caucasian

1.0982

[0.92–1.29]

0.27

0.1489

0.3855

0.5338

Quality of the study

1.5363

[0.92–2.55]

0.0967

NA

NA

NA

CC + CT vs. TT

Overall

0.8024

[0.58–1.10]

0.17928

0.6291

0

0.8515

East Asian

0.4813

[0.23–1.00]

0.0518

0.8723

0

0.4451

South Asian

5.6331

[0.3008; 105.4861]

0.2475

NA

NA

NA

Caucasian

0.8538

[0.52–1.39]

0.5264

0.3652

0.08

0.7439

Quality of the study

0.2761

[0.05–1.35]

0.1121

NA

NA

NA

CT vs. CC + TT

Overall

0.9525

[0.85–1.06]

0.37577

0.0019

0.6143

0.7475

East Asian

1.5047

[1.19–1.90]

0.0006

0.4893

0

0.1881

South Asian

0.8515

[0.51–1.41]

0.5325

NA

NA

NA

Caucasian

0.8843

[0.74–1.04]

0.1603

0.1346

0.4061

0.4246

Quality of the study

0.5252

[0.30–0.89]

0.0177

NA

NA

NA

CC vs. CT

Overall

1.0426

[0.93–1.16]

0.45

0.001

0.634

0.7373

East Asian

0.6478

[0.51–0.81]

0.0002

0.4897

0

0.1603

South Asian

1.2055

[0.72–1.99]

0.46867

NA

NA

NA

Caucasian

1.1245

[0.94–1.33]

0.1824

0.1323

0.4095

0.4483

Quality of the study

1.8293

[1.07–3.12]

0.0268

NA

NA

NA