Variable | Cases n = 60 | EGFR L858R mutation (n = 60) | OR (95% CI) | P value | |
---|---|---|---|---|---|
Mutants n = 26 (43.3%) | Wild type n = 34 (56.7%) | ||||
Gender |  |  |  | 1.4(0.4–4.5) | 0.52 |
 Female | 44(73.0) | 18(41.0) | 26(59.0) |  |  |
 Male | 16(27.0) | 08(50.0) | 08(50.0) |  |  |
Age in years |  |  |  | 0.5(0.16–1.9) | 0.36 |
 < 45 | 45(75.0) | 21(46.6) | 24(53.4) |  |  |
 ≥ 45 | 15(25.0) | 05(33.4) | 10(66.6) |  |  |
Habitation |  |  |  | 0.3(0.06–1.7) | 0.27 |
 Rural | 51(85.0) | 24(47.0) | 27(53.0) |  |  |
 Urban | 09(15.0) | 02(22.3) | 07(77.7) |  |  |
Marital status |  |  |  | 3.0(1.1–9.1) | 0.04* |
 Unmarried | 25(41.6) | 07(28.0) | 18(72.0) |  |  |
 Married | 35(53.4) | 19(54.3) | 16(45.7) |  |  |
Use of OCP |  |  |  | 0.5(0.07–3.1) | 0.64 |
 Yes | 05(8.4) | 03(60.0) | 02(40.0) |  |  |
 No | 55(91.6) | 23(41.8) | 32(58.2) |  |  |
Smoking status |  |  |  | 0.8(0.2–3.3) | 1.00 |
 Non-smoker | 50(83.4) | 22(44.0) | 28(56.0) |  |  |
 Smoker | 10(16.6) | 04(40.0) | 06(60.0) |  |  |
TSH levels |  |  |  | 0.7(0.25–1.9) | 0.49 |
 Elevated | 27(45.0) | 13(48.1) | 14(51.9) |  |  |
 Normal | 33(55.0) | 13(39.3) | 20(60.7) |  |  |
Serum calcium |  |  |  | 1.5(0.5–4.4) | 0.46 |
 Normal | 40(66.6) | 16(40.0) | 24(60.0) |  |  |
 Decreased | 20(33.4) | 10(50.0) | 10(50.0) |  |  |
Initial PPX |  |  |  | 0.9(0.1–5.5) | 1.00 |
 Swelling | 55(91.6) | 24(43.6) | 31(56.4) |  |  |
 Incidental detection | 05(8.4) | 02(40.0) | 03(60.0) |  |  |
BTD |  |  |  | 3.3(0.3–31.7) | 0.37 |
 Yes | 05(80.0) | 01(20.0) | 04(80.0) |  |  |
 No | 55(20.0) | 25(45.5) | 30(54.5) |  |  |
Histological types |  |  |  | 0.9(0.25–3.3) | 0.89 |
 Papillary | 48(80.0) | 21(43.7) | 27(56.3) |  |  |
 Follicular | 12(20.0) | 05(41.6) | 07(58.4) |  |  |
Grade |  |  |  | 3.3(1.0–10.2) | 0.03* |
 WD | 41(68.4) | 14(34.2) | 27(65.8) |  |  |
 PD | 19(31.6) | 12(63.2) | 07(36.8) |  |  |
Stage, < 45 years |  |  |  | 2.3(0.7–7.3) | 0.007* |
 Stage I | 28(46.6) | 12(42.8) | 16(57.2) |  |  |
 Stage II | 17(28.4) | 14(82.3) | 08(17.6) |  |  |
Stage, ≥ 45years |  |  |  | 1.0(0.1–8.9) | 1.00 |
 Stages I and II | 09(15.0) | 03(33.4) | 06(66.6) |  |  |
 Stage III and above | 06(10.0) | 02(33.4) | 04(66.6) |  |  |
V/C invasion |  |  |  | 0.9(0.3–2.6) | 0.94 |
 Present | 32(53.4) | 14(43.7) | 18(56.3) |  |  |
 Absent | 28(46.6) | 12(42.8) | 16(57.2) |  |  |
LN metastasis |  |  |  | 2.3(0.7–7.6) | 0.17 |
 Present | 17(28.4) | 05(29.5) | 12(70.5) |  |  |
 Absent | 43(71.6) | 21(48.8) | 22(51.2) |  |  |